3-Butyl-6,6,9-trimethyl-6a,7,8,10a-tetrahydrobenzo[c]chromen-1-ol

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 苯并吡喃
• 英文名称: 3-Butyl-6,6,9-trimethyl-6a,7,8,10a-tetrahydrobenzo[c]chromen-1-ol
• 化学式: C₂₀H₂₈O₂
• 分子量: 300.4
• InChiKey: QHCQSGYWGBDSIY-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  6.4
• 重原子数：
  22
• 可旋转键数：
  3
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.6
• 拓扑面积：
  29.5
• 氢给体数：
  1
• 氢受体数：
  2

文献信息

• Prenyltransferase variants with increased thermostability
  申请人：INVIZYNE TECHNOLOGIES, INC.

  公开号：US11518983B1

  公开（公告）日：2022-12-06

  The present disclosure relates to recombinant prenyltransferase enzymes with increased thermostability and activity and the use of these enzymes in compositions and methods for biosynthesis involving prenylation reactions, including compositions and methods for the preparation of cannabinoids.

  本公开涉及具有更高热稳定性和活性的重组炔基转移酶，以及这些酶在涉及炔基 化反应的生物合成的组合物和方法中的用途，包括制备大麻素的组合物和方法。
• STABLE FORMULATIONS OF DRONABINOL
  申请人：TRYAGx Labs Inc.

  公开号：US20210251947A1

  公开（公告）日：2021-08-19

  Described herein are formulations, methods of manufacturing, and methods of treatment using formulations of cannabinoids that are stable at room temperature for at least about one to two years. In one embodiment, the composition is an oxidatively stable formulation of dronabinol.
• RECOMBINANT ACYL ACTIVATING ENZYME (AAE) GENES FOR ENHANCED BIOSYNTHESIS OF CANNABINOIDS AND CANNABINOID PRECURSORS
  申请人：Willow Biosciences, Inc.

  公开号：US20220186231A1

  公开（公告）日：2022-06-16

  The present disclosure provides recombinant host cells comprising a pathway capable of producing a cannabinoid and/or cannabinoid precursor, wherein the pathway comprises an enzyme AAE from a source organism other than Cannabis sativa , such as Humulus lupulus . The disclosure also provides methods of using the host cells to produce rare cannabinoids and/or rare cannabinoid precursors.
• PRENYLTRANSFERASE VARIANTS WITH INCREASED THERMOSTABILITY
  申请人：INVIZYNE TECHNOLOGIES, INC.

  公开号：US20220403349A1

  公开（公告）日：2022-12-22

  The present disclosure relates to recombinant prenyltransferase enzymes with increased thermostability and activity and the use of these enzymes in compositions and methods for biosynthesis involving prenylation reactions, including compositions and methods for the preparation of cannabinoids.
• [EN] CANNABIS OIL COMPOSITIONS AND METHODS FOR PREPARATION THEREOF<br/>[FR] COMPOSITIONS D'HUILE DE CANNABIS ET LEURS PROCÉDÉS DE PRÉPARATION
  申请人：CONSTANCE THERAPEUTICS INC

  公开号：WO2017091764A1

  公开（公告）日：2017-06-01

  The present invention provides cannabis oil compositions, including cannabis oil compositions containing vitamin E, and methods for preparing the cannabis oil compositions. In some embodiments, the invention provides a method for preparing a cannabis oil composition comprising eluting cannabinoids from cannabis plant material with a solvent to produce an eluate; filtering the eluate with a filter to produce a filtrate; evaporating the solvent from the filtrate with a distiller to produce a distillate; and purging the distillate under conditions sufficient to remove residual solvent. In some embodiments, the method further includes mixing a quantity of vitamin E with the extract. Blended cannabis oil compositions containing mixtures of cannabis oil preparations are also described.