ε-Pyrromycinon | 54773-77-2

• 分子结构分类: 有机化合物 - 苯类化合物 - 并四苯
• 英文名称: ε-Pyrromycinon
• 英文别名: Eta-Pyrromycinon；methyl 2-ethyl-2,4,5,7,10-pentahydroxy-6,11-dioxo-3,4-dihydro-1H-tetracene-1-carboxylate
• CAS: 54773-77-2
• 化学式: C₂₂H₂₀O₉
• 分子量: 428.395
• InChiKey: RWCVSDKDFSVZNF-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.7
• 重原子数：
  31
• 可旋转键数：
  3
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.32
• 拓扑面积：
  162
• 氢给体数：
  5
• 氢受体数：
  9

反应信息

• 作为产物：
  描述：

  methyl 4-[(2S,4S,5R,6R)-4-(dimethylamino)-5-[(2S,4S,5S)-4-hydroxy-5-[(2R,6R)-6-methyl-5-oxooxan-2-yl]oxyoxan-2-yl]oxy-6-methyloxan-2-yl]oxy-2-ethyl-2,5,7,10-tetrahydroxy-6,11-dioxo-3,4-dihydro-1H-tetracene-1-carboxylate 生成 ε-Pyrromycinon
  参考文献：
  名称：

  FROLOVA, V. I.;KUZOVKOV, A. D.;ROZYNOV, B. V.;TAJG, M. M.;IVANITSKAYA, L.+, ANTIBIOTIKI, 1982, 27, N 5, 326-331

  摘要：

  DOI：

文献信息

• Molecular sensors and uses thereof
  申请人：New York University

  公开号：US11242555B2

  公开（公告）日：2022-02-08

  The present disclosure provides molecular sensors. The molecular sensors may be flexible or linear and are oligonucleotide-based and have fluorescent groups. The molecular sensors may be used in methods to measure molecular crowding, identify of binding modes of various substrates, pharmaceutical drug screens, and in high-throughput methods.

  本公开提供分子传感器。分子传感器可以是柔性或线性的，以寡核苷酸为基础并带有荧光基团。分子传感器可用于测量分子拥挤度、识别各种底物的结合模式、药物筛选和高通量方法。
• MOLECULAR SENSORS AND USES THEREOF
  申请人：New York University

  公开号：US20200095627A1

  公开（公告）日：2020-03-26

  The present disclosure provides molecular sensors. The molecular sensors may be flexible or linear and are oligonucleotide-based and have fluorescent groups. The molecular sensors may be used in methods to measure molecular crowding, identify of binding modes of various substrates, pharmaceutical drug screens, and in high-throughput methods.