Viridicatumtoxin

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 四环素类
• 英文名称: Viridicatumtoxin
• 英文别名: 5,6,7a,10,11a,12-hexahydroxy-3-methoxy-2',6',6'-trimethyl-7,8-dioxo-7,7a,8,11,11a,12-hexahydro-1H-spiro[cyclohexa[k]aceanthrylene-2,1'-cyclohexan]-2'-ene-9-carboxamide
• 化学式: C30H31NO10
• InChiKey: SUWQGLGDFGHZNH-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.78
• 重原子数：
  41.0
• 可旋转键数：
  2.0
• 环数：
  6.0
• sp3杂化的碳原子比例：
  0.43
• 拓扑面积：
  207.84
• 氢给体数：
  7.0
• 氢受体数：
  10.0

文献信息

• NOVEL COMPOUND, PROCESS FOR PRODUCTION THEREOF, AND USE THEREOF
  申请人：Tomoda Hiroshi

  公开号：US20100291622A1

  公开（公告）日：2010-11-18

  The present invention provides compounds which exhibit an inhibitory effect on undecaprenyl diphosphate synthase of microbes and thereby they are expected to be used clinically as pharmaceutical agents for infectious diseases caused by bacteria. The process comprises culturing a microbe belonging to Penicillium and having ability of producing an FKI-3368 substance in or on a nutrient medium to accumulate the FKI-3368 substance in the nutrient medium and collecting the FKI-3368 substance from the culture.