8,9-Dihydro-1-hydroxy-6,6,9-trimethyl-3-pentyl-6H-dibenzo(B,D)pyran-10(7H)-one | 56154-60-0

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 苯并吡喃
• 英文名称: 8,9-Dihydro-1-hydroxy-6,6,9-trimethyl-3-pentyl-6H-dibenzo(B,D)pyran-10(7H)-one
• 英文别名: 1-hydroxy-6,6,9-trimethyl-3-pentyl-8,9-dihydro-7H-benzo[c]chromen-10-one
• CAS: 56154-60-0
• 化学式: C₂₁H₂₈O₃
• 分子量: 328.4
• InChiKey: UEFGHYCIOXYTOG-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.9
• 重原子数：
  24
• 可旋转键数：
  4
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.57
• 拓扑面积：
  46.5
• 氢给体数：
  1
• 氢受体数：
  3

文献信息

• Bioactive concentrates and uses thereof
  申请人：SC LABORATORIES, INC.

  公开号：US10792318B2

  公开（公告）日：2020-10-06

  The present invention relates to concentrates obtained from extraction from Cannabis, preferably cannabinoid and/or terpene concentrates, and formulation of the concentrates, particularly for use for direct vaporization, infusion into edible matrices, in electronic inhalation devices, and as nutraceuticals.

  本发明涉及从大麻中提取的浓缩物，最好是大麻素和/或萜类浓缩物，以及浓缩物的配方，特别是用于直接汽化、注入可食用基质、电子吸入装置和作为营养保健品。
• Recombinant production systems for prenylated polyketides of the cannabinoid family
  申请人：BayMedica, Inc.

  公开号：US10837031B2

  公开（公告）日：2020-11-17

  The present invention relates generally to production methods, enzymes and recombinant yeast strains for the biosynthesis of clinically important prenylated polyketides of the cannabinoid family. Using readily available starting materials, heterologous enzymes are used to direct cannabinoid biosynthesis in yeast.

  本发明一般涉及生产方法、酶和重组酵母菌株，用于生物合成临床上重要的大麻素家族前烯化多酮类化合物。利用现成的起始材料，异源酶被用来指导酵母中大麻素的生物合成。
• Apparatus and methods for sample analysis and classification based on terpenes and cannabinoids in the sample
  申请人：Biotech Institute, LLC

  公开号：US10830780B2

  公开（公告）日：2020-11-10

  The disclosure relates to systems, apparatuses, and methods for estimating a terpene level of two or more terpenes of the plurality of terpenes in the sample to generate a set of terpene levels; and/or estimating a cannabinoid level of two or more cannabinoids of the plurality of cannabinoids in the sample to generate a set of cannabinoid levels; configured to store a set of groups and classify the sample to a group of the set of groups, based on said terpene and cannabinoid levels. The present disclosure also relates to systems, apparatuses, and methods configured to generate entourage effect values and organoleptic values, based on said cannabinoid and terpene levels.

  本公开涉及系统、装置和方法，用于估算样品中多种萜烯中两种或多种萜烯的萜烯含量，以生成一组萜烯含量；和/或估算样品中多种大麻素中两种或多种大麻素的大麻素含量，以生成一组大麻素含量；根据所述萜烯和大麻素含量，配置为存储一组组别并将样品分类到组别中的一组。本公开还涉及根据所述大麻素和萜烯含量生成随附效应值和感官值的系统、装置和方法。
• Biosynthesis of cannabinoids and cannabinoid precursors
  申请人：Ginkgo Bioworks, Inc.

  公开号：US11274320B2

  公开（公告）日：2022-03-15

  Aspects of the disclosure relate to biosynthesis of cannabinoids and cannabinoid precursors in recombinant cells and in vitro.

  本公开的各个方面涉及在重组细胞和体外进行大麻素和大麻素前体的生物合成。
• Methods and compositions for treating cancer
  申请人：Sutter West Bay Hospitals

  公开号：US11344527B2

  公开（公告）日：2022-05-31

  This disclosure provides compositions and method useful for treating cell proliferative disorders including cancer. The disclosure provides cannabidiol derivatives and compositions thereof either alone or in combination with THC or a derivative thereof.

  本公开提供了用于治疗包括癌症在内的细胞增殖性疾病的组合物和方法。本公开提供了大麻二酚衍生物及其单独或与四氢大麻酚或其衍生物结合使用的组合物。