iron(II) carbonate | 767234-62-8

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 有机碳酸及其衍生物
• 英文名称: iron(II) carbonate
• 英文别名: iron carbonate；ferrous carbonate；iron(2+);carbonate
• CAS: 767234-62-8
• 化学式: CO₃*Fe
• 分子量: 115.856
• InChiKey: RAQDACVRFCEPDA-UHFFFAOYSA-L

物化性质

• 颜色/状态：
  Precipitates as a white solid
• 溶解度：
  0.0067 G SOL IN 1 LITER OF WATER @ 25 °C; SOL IN CARBONIC ACID SOLUTION
• 密度：
  3.9 g/cu cm

计算性质

• 辛醇/水分配系数(LogP)：
  -2.45
• 重原子数：
  5
• 可旋转键数：
  0
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  63.2
• 氢给体数：
  0
• 氢受体数：
  3

ADMET

毒理性

• 相互作用

16头公荷斯坦牛犊在实验中接受了四种不同的饮食，持续18天，实验包括0和1000 ppm补充的锰以及0和1000 ppm添加的铁，形式为碳酸锰和碳酸亚铁。对照组饮食中含有55 ppm锰和220 ppm铁。所有牛犊在宰杀前48小时口服了500微居里的锰-54。喂食高锰饮食的牛犊的小肠铁含量较低，可能是这两种元素在吸收位点相互作用的可能。喂食高锰饮食倾向于降低肝脏和胰腺中铁（总量）的浓度。当高锰饮食中补充了额外的铁时，锰对铁的拮抗作用被消除。组织中的铁或锰浓度并未受到饮食中铁增加的影响。高锰饮食减少了组织的锰-54含量，但并未受到饮食中铁的影响。粪便中的总锰和铁相当准确地反映了每种元素的饮食摄入量，没有相互作用的证据。喂食高铁饮食的牛犊在两天内通过粪便排出的锰-54较少。饮食处理对血液血清中的总铁含量没有显著影响。

Sixteen male Holstein calves were fed one of four diets for 18 days in an experiment consisting of 0 and 1000 ppm supplemental manganese and 0 and 1000 ppm added iron as manganese carbonate and ferrous carbonate. The control diet contained 55 ppm manganese and 220 ppm iron. All calves were dosed orally 48 hr prior to sacrifice with 500 muCi of manganese-54. Small intestinal iron was less in calves fed a high manganese diet, a possible interaction of these two elements at the absorption site. Feeding a high manganese diet tended to decrease iron (total) concentrations in liver and pancreas. When the high manganese diet was supplemented with additional iron, antagonistic effects of manganese on iron were eliminated. Neither iron nor manganese concentrations in tissues were affected by an increase of dietary iron. Manganese-54 content of tissue was reduced by the high manganese diet but was not affected by dietary iron. Total manganese and iron in feces fairly closely reflected dietary intake of each element with no evidence of interaction. Calves fed the high iron diet excreted less manganese-54 in their feces over 2 days. Total iron in blood serum was not affected significantly by the dietary treatments.

来源:Hazardous Substances Data Bank (HSDB)

毒理性

• 相互作用

液体抗酸药对铁片中铁吸收的影响在健康志愿者中通过血清铁技术进行了研究。研究了含有二价铁盐（碳酸铁、富马酸铁、硫酸铁）的片剂，这些铁盐具有不同的体外溶解特性。同时给予抗酸药和铁片剂导致所有研究的制剂中铁的吸收显著减少。当碳酸铁与抗酸药一起服用时，发现吸收率最低。这归因于碳酸铁在接近中性的pH水平下几乎完全不溶解。这一发现在一组患有胃酸缺乏的患者的系列研究中得到了证实，其中碳酸铁的吸收几乎为零。

The influence of a liquid antacid on the absorption of iron from iron tablets was studied in healthy volunteers using a serum iron technique. Tablets containing ferrous salts (carbonate, fumarate, sulfate) with different in-vitro dissolution properties were studied. Co-administration of the antacid and the iron tablets resulted in a marked reduction of the absorption of iron from all preparations studied. The lowest absorption was found when ferrous carbonate was given with the antacid. This was ascribed to the fact that ferrous carbonate is almost completely insoluble at pH-levels near neutral. This was confirmed in a series of patients with achlorhydria in which the absorption from ferrous carbonate was virtually nil.

来源:Hazardous Substances Data Bank (HSDB)

毒理性

• 解毒与急救

基本治疗：建立专利气道。如有必要，进行吸痰。观察呼吸不足的迹象，如有必要，协助通气。通过非循环呼吸面罩以10至15升/分钟的速度给予氧气。监测休克并视需要进行治疗……。对于眼睛污染，立即用水冲洗眼睛。在运输过程中，用生理盐水连续冲洗每只眼睛……。不要使用催吐剂。对于摄入，如果患者能够吞咽，有强烈的呕吐反射，并且不流口水，用水冲洗口腔，并给予5毫升/千克，最多200毫升的水进行稀释。/铁及其相关化合物/

Basic treatment: Establish a patent airway. Suction if necessary. Watch for signs of respiratory insufficiency and assist ventilations if necessary. Administer oxygen by nonrebreather mask at 10 to 15 L/min. Monitor for shock and treat if necessary ... . For eye contamination, flush eyes immediately with water. Irrigate each eye continuously with normal saline during transport ... . Do not use emetics. For ingestion, rinse mouth and administer 5 ml/kg up to 200 ml of water for dilution if the patient can swallow, has a strong gag reflex, and does not drool. /Iron and related compounds/

来源:Hazardous Substances Data Bank (HSDB)

毒理性

• 解毒与急救

高级治疗：对于无意识的病人，考虑进行口咽或鼻咽气管插管以控制气道。监测心率和必要时治疗心律失常。开始静脉输液，使用乳酸钠林格氏液/生理盐水： "保持开放"，最低流速。注意液体过载的迹象。对于伴有低血容量症状的低血压，谨慎给予液体。注意液体过载的迹象。使用丙美卡因氢氯化物协助眼部冲洗。/铁及其相关化合物/

Advanced treatment: Consider orotracheal or nasotracheal intubation for airway control in the patient who is unconscious. Monitor cardiac rhythm and treat arrhythmias if necessary ... . Start an IV with lactated Ringer's /SRP: "To keep open", minimal flow rate/. Watch for signs of fluid overload. For hypotension with signs of hypovolemia, administer fluid cautiously. Watch for signs of fluid overload ... . Use proparacaine hydrochloride to assist eye irrigation ... . /Iron and related compounds/

来源:Hazardous Substances Data Bank (HSDB)

毒理性

• 解毒与急救

保持呼吸道通畅，必要时协助通气。积极使用静脉晶体液治疗由出血性胃肠炎引起的休克，并在需要时输血。由于胃肠道丢失和液体进入肠壁和间质空间的第三间隙，患者常常出现明显的低血容量。如果出现昏迷、癫痫和代谢性酸中毒，则进行治疗。对于严重中毒的患者（例如，休克、严重酸中毒和/或血清铁> 500-600 mcg/dL），给予去铁胺。监测尿液，以发现特征性的橙色或粉红色去铁胺-铁复合物。当尿液恢复正常或血清铁水平降至正常范围时，可以停止治疗。长期使用去铁胺与成人呼吸窘迫综合征和耶尔森菌血症有关。

Maintain an open airway and assist ventilation if necessary. Treat shock caused by hemorrhagic gastrointestinitis aggressively with intravenous crystalloid fluids, and replace blood if needed. Patients are often markedly hypovolemic owing to gastrointestinal losses and third spacing of fluids into the intestinal wall and interstitial space. Treat coma, seizures, and metabolic acidosis if they occur. For seriously intoxicated victims (eg, shock, severe acidosis, and/or serum iron > 500-600 mcg/dL) administer deferoxamine. Monitor the urine for the urine for the characteristic orange or pink deferoxamine-iron complex. Therapy may be stopped when the urine returns to normal or when the serum iron level decreases to the normal range. Prolonged deferoxamine has been associated with adult respiratory distress syndrome and Yersinia sepsis.

来源:Hazardous Substances Data Bank (HSDB)

吸收、分配和排泄

胃肠对铁的吸收是足够的...然而...从碳酸亚铁的吸收率...低于硫酸亚铁、富马酸亚铁、葡萄糖酸亚铁、琥珀酸亚铁、谷氨酸亚铁和乳糖亚铁。

Gastrointestinal absorption of iron is adequate.../yet/...lower from...ferrous carbonate.../than ferrous sulfate, fumarate, gluconate, succinate, glutamate, and lactate/.

来源:Hazardous Substances Data Bank (HSDB)

吸收、分配和排泄

正常人类男性口服硫酸亚铁或碳酸亚铁的测试剂量分别为10毫克或100毫克时，铁的吸收没有发现差异。

No differences were found in iron absorption by normal human males given oral test doses of 10 or 100 mg ferrous sulfate or ferrous carbonate, respectively.

来源:Hazardous Substances Data Bank (HSDB)

吸收、分配和排泄

24只平均体重为29公斤的羔羊被用来确定补充日粮铁（Fe）对性能以及铜（Cu）、磷（P）、锌（Zn）和锰（Mn）利用率的影响。处理方法包括以碳酸亚铁的形式补充0、300、600或1200毫克/公斤日粮的铁。基础日粮含有154毫克铁/公斤日粮，由90%的海滨百慕大草颗粒、9.45%的组玉米、0.5%的氯化钠和0.05%的维生素混合物组成。羔羊在自由采食98至121天的日粮后被屠宰。日粮铁对羔羊的体重增加或饲料摄入量没有影响。补充铁增加了肝脏（P<0.01）、脾脏（P<0.01）和骨骼（P<0.10）中铁的浓度，但对肾脏和肌肉没有影响。血清铁浓度和血清转铁蛋白饱和度在28天和84天时因补充铁而增加（P<0.01），但在研究结束时没有增加。在56天时，补充1200毫克铁/公斤日粮的羔羊的血浆铜含量降低（P<0.01），而在28天时，血清铜蓝蛋白活性较补充600毫克铁/公斤日粮的羔羊降低（P<0.01）。较低水平的铁（300和600毫克）在56天时减少了铜蓝蛋白（P<0.01），在84天时减少了血浆铜（P<0.01），与对照组相比。补充铁还降低了肝脏铜（P<0.05）。在28天时，血浆磷略有下降（P<0.10），在其他采样日期显著下降（P<0.01）。

Twenty-four lambs, averaging 29 kg, were used to determine the effect of supplemental dietary Fe on performance and Cu, P, Zn and Mn utilization. Treatments consisted of supplemental Fe at 0, 300, 600 or 1,200 mg/kg diet as ferrous carbonate. The basal diet contained 154 mg Fe/kg diet and consisted of 90% Coastal bermudagrass pellets, 9.45% group corn, .5% sodium chloride and .05% vitamin mix. Lambs were slaughtered after having ad libitum access to diets for 98 to 121 days. Dietary Fe did not affect lamb /weight/ gain or feed intake. Supplemental Fe increased Fe concentrations in liver (P<0.01), spleen (P<0.01) and bone (P<0.10), but not in kidney and muscle. Serum Fe concentrations and percentage transferrin saturation in serum were increased (P<0.01) by supplemental Fe at 28 and 84 days, but not at the termination of the study. Plasma Cu was decreased (P<0.01) at 56 days, whereas serum ceruloplasmin activity was reduced (P<0.01) at 28 days in lambs fed 1,200 mg Fe/kg diet compared with lambs fed 600 mg Fe/kg diet. Lower levels of Fe (300 and 600) reduced (P<0.01) ceruloplasmin by 56 days and plasma Cu by 84 days compared with controls. Liver Cu also was decreased (P<0.05) by supplemental Fe. Plasma P was decreased slightly (P<0.10) by 28 days and significantly (P<0.01) at the other sampling dates by supplemental Fe.

来源:Hazardous Substances Data Bank (HSDB)

反应信息

• 作为反应物：
  描述：

  iron(II) carbonate 在 氮气 作用下， 以 neat (no solvent) 为溶剂， 生成 iron(II) oxide
  参考文献：
  名称：

  Simultaneous TG, DTG, DTA and EGA examination of argillaceous rocks. Part I

  摘要：

  DOI：

  10.1007/bf01911672
• 作为产物：
  描述：

  iron(II) hydrogen carbonate 以 水 为溶剂， 生成 iron(II) carbonate
  参考文献：
  名称：

  Golfier-Besseyre, Annales de Chimie et de Physique, 1851, vol. 32, p. 431 - 431

  摘要：

  DOI：
• 作为试剂：
  描述：

  alkaline earth salt of/the/ methylsulfuric acid 在 iron(II) carbonate 作用下， 生成 potassium cyanate
  参考文献：
  名称：

  DE175583

  摘要：

  公开号：

文献信息

• MCC: Specific of preparation, correlation of the phase composition and electrodynamic properties
  作者：D.S. Klygach、M.G. Vakhitov、D.A. Pankratov、D.A. Zherebtsov、D.S. Tolstoguzov、Z. Raddaoui、S. El Kossi、J. Dhahri、D.A. Vinnik、A.V. Trukhanov

  DOI：10.1016/j.jmmm.2020.167694

  日期：2021.5

  Ce-based composites respectively. The electrodynamic properties of the MCCs in the Extremely High Frequency range (30-50 GHz) were studied as function of the filler concentration. The frequency dependences of the permittivity and permeability (real and imaginary parts) of the investigated composites were measured. The nature of the MCC electrodynamic properties was discussed in detail in terms of polarization

  金属碳复合材料（MCC）是通过将硝酸铁，钴和铈的硝酸盐溶解在酚醛树脂中并进一步热解（加热至800°C）制得的。最终MCC中金属组合物的浓度为2、7和15重量％。使用XRD和Mössbauer光谱法确定最终MCC样品的相组成。由于与酚醛分解产物的化学相互作用，在热解过程中金属化合物中已建立相分离。复合材料的主要相为：Fe 3 O 4（对于MCC-Fe）；Co（用于MCC-Co）和CeO 2（对于MCC-Ce）。金属基填料的平均晶体尺寸为Fe-，分别为28、24-35和3.5 nm。钴和铈基复合材料。研究了MCC在极高频率范围（30-50 GHz）中的电动力学性质，它是填料浓度的函数。测量了所研究复合材料的介电常数和磁导率（实部和虚部）的频率依赖性。MCC电动力学性质的性质已根据极化损耗进行了详细讨论。
• METHOD FOR PRODUCING METAL CARBONATE AND CATALYST FOR PRODUCING THE SAME
  申请人：TaiGreen Science Inc.

  公开号：US20170217786A1

  公开（公告）日：2017-08-03

  A method for producing metal carbonate is disclosed. The method includes the following steps of providing a first mixture of metal and a catalyst containing iron, NO groups, and N-containing ligands first; then introducing carbon dioxide to the first mixture to form a second mixture and obtaining a product. The method described here can improve the yield and decrease the cost of metal carbonate production.

  公开了一种生产金属碳酸盐的方法。该方法包括以下步骤：首先提供含有铁、NO基团和含氮配体的金属和催化剂的第一混合物；然后将二氧化碳引入第一混合物以形成第二混合物并获得产品。这里描述的方法可以提高金属碳酸盐生产的产量并降低成本。
• Isolation of a tetranuclear iron cluster promoting CO2 reduction and intermediate to iron carbonyl disproportionation
  作者：Giuseppe Fachinetti、Giovanni Fochi、Tiziana Funaioli、Pier Francesco Zanazzi

  DOI：10.1039/c39870000089

  日期：——

  (py)Fe(CO)4(py = pyridine) is formed on carbonylation of [Fe(py)6][Fe4(CO)13], and the 56 electron tetranuclear cluster [(py)2FeFe(CO)4]2, the crystal structure of which has been determined, is produced on dissolving (py)Fe(CO)4 in organic solvents; it behaves as a bifunctional molecule in reducing CO2 to CO, FeCO3 being formed during this reaction.

  在[Fe（py）6 ] [Fe 4（CO）13 ]和56电子四核簇[[py）2 FeFe（CO）4的羰基化反应中形成（py）Fe（CO）4（py =吡啶）通过将（py）Fe（CO）4溶解在有机溶剂中，制得已确定晶体结构的] 2；它在将CO 2还原为CO时起双功能分子的作用，在该反应过程中会生成FeCO 3。
• Kinetics of thermal decomposition of iron(III) dicarboxylate complexes
  作者：R. Prasad、Sulaxna、A. Kumar

  DOI：10.1007/s10973-005-0804-5

  日期：2005.7

  bis chelate iron(III) complexes. The trismalonato and trismaleato complexes dehydrate with almost equal ease but the latter is much less stable to decomposition and yields FeCO3 below 760 K. The cis -dicarboxylate complexes particularly with maleate(2-) and phthalate(2-) ligands are highly prone to the loss of cyclic anhydrides at moderately raised temperatures. The thermal decomposition of the tri

  铁（III）与草酸酯，马来酸酯，丙二酸酯和邻苯二甲酸酯的三（二羧酸酯）配合物。K 3 [Fe（C 2 O 4）3 ]×3H 2 O（ 1 ），K 3 [Fe（OOCCH 2 COO）3 ]×3H 2 O（ 2 ），K 3 [Fe（OOCCH = CHCOO）3 ] ×3H 2 O（ 3 ），K 3 [Fe（OOC-1,2-（C 6 H 4）-COO）3 ]×3H 2 O（ 4 ）已结合理化技术进行了合成和表征。在高达800 K的动态空气气氛下研究了这些配合物的热分解行为。所有这些配合物均经过三步脱水/分解过程，其动力学参数已使用Freeman-Carrol模型以及不同的机理模型进行了计算。固态反应。在低于470 K的较低温度下，高铁三草酸酯和高铁Trismalonato（III）配合物会快速脱水。在较高的温度下（分别分别> 600和500 K），它们会形成双螯合铁（III）配合物。Tris
• Non-isothermal dehydration and decomposition of dl-lactates of transition metals and alkaline earth metals
  作者：R. K. Verma、L. Verma、M. Chandra、A. Bhushan

  DOI：10.1007/s10973-005-0659-9

  日期：2005.5

  study of the non-isothermal decomposition of the dl -lactate hydrates of magnesium, calcium and strontium has been made with that of the dl -lactate hydrates chromium(III), manganese(II), iron(II), cobalt(II), nickel(II), copper(II) and zinc(II) keeping dry air as the purge gas and the heating rate maintained at 10 K min-1. While the dl -lactates of manganese(II), cobalt(II) and copper(II) followed

  所述的非等温分解的比较研究 DL 镁，钙和锶的乳酸盐水合物已取得了的 DL -乳水合物铬（III），锰（II），铁（II），钴（II ），镍（II），铜（II）和锌（II）保持干燥的空气作为吹扫气体，加热速率保持在10 K min -1。尽管锰（II），钴（II）和铜（II）的 dl- 乳酸盐遵循单步分解方案，表明脱水和分解步骤重叠，但其他化合物的脱水步骤却截然不同。＆AGR; - Ť 没有一个脱水步骤的曲线显示任何诱导期，表明没有物理解吸，成核或分支。＆agr;都不 最大值和脱水步骤的起始温度均未显示任何模式。还使用Freeman-Carroll，Horowitz-Metzger，Coats-Redfern，Zsak＆oacute;，Fuoss-Salyer-Wilson和Karkhanavala-Dharwadkar方法分析了脱水步骤的TG数据。反应阶数，活化能和阿累尼乌斯因子的值已被