[(1R,10S,12R,13E,14R,16S)-13-Ethylidene-14-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-8,15-diazahexacyclo[14.2.1.01,9.02,7.010,15.012,17]nonadeca-2,4,6,8-tetraen-18-yl] acetate | 31282-07-2

• 物质功能分类: 天然产物 - 生物碱
• 分子结构分类: 有机化合物 - 生物碱及其衍生物 - 可吗灵-沙巴秦生物碱
• 英文名称: [(1R,10S,12R,13E,14R,16S)-13-Ethylidene-14-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-8,15-diazahexacyclo[14.2.1.01,9.02,7.010,15.012,17]nonadeca-2,4,6,8-tetraen-18-yl] acetate
• CAS: 31282-07-2
• 化学式: C₂₇H₃₂N₂O₈
• 分子量: 512.6
• InChiKey: OSJPGOJPRNTSHP-BGYCQZOHSA-N

物化性质

• 密度：
  1.75±0.1 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  -0.2
• 重原子数：
  37
• 可旋转键数：
  5
• 环数：
  8.0
• sp3杂化的碳原子比例：
  0.63
• 拓扑面积：
  141
• 氢给体数：
  4
• 氢受体数：
  10

文献信息

• PLANT GENES INVOLVED IN DEFENSE AGAINST PATHOGENS
  申请人：Syngenta Participations AG

  公开号：EP1402037A1

  公开（公告）日：2004-03-31
• POWDERED POUCH AND METHOD OF MAKING SAME
  申请人：Monosol, LLC

  公开号：EP2838811A1

  公开（公告）日：2015-02-25
• EP3201100A2
  申请人：——

  公开号：EP3201100A2

  公开（公告）日：2017-08-09
• BETA-GLUCOSIDASE AND A PROCESS FOR EXTRACTION THEREOF
  申请人：Sangwan Neelam Singh

  公开号：US20070212745A1

  公开（公告）日：2007-09-13

  The present invention provides a novel beta glucosidase and a process for extraction of a beta-glucosidase from Rauvolfia serpentine useful for the cleaving of beta-1,4 linkage of PNPG and to convert other gluco-conjugates such as strictosidine and raucaffricine into their corresponding aglycon such as vomilenine, commercially through immobilizing the enzyme. The β glucosidase enzyme has shown maximum activity in the acid pH range, with high optimum temperature using PNPG as substrate. The crude enzyme, when stored at 4° C., was quite stable for 6 days with 50% loss of activity. The enzyme was activated in presence of FeSO 4 in the assay mixture.
• Cell-Mediated Directed Evolution
  申请人：Cornish Virginia W.

  公开号：US20090209038A1

  公开（公告）日：2009-08-20

  The present invention relates to systems which harness the molecular biology of a living cell to direct evolution of biological entities of interest. According to the invention, a host cell is engineered to facilitate mutation of a nucleic acid target corresponding to that entity and select for desirable mutants. As applied to populations of host cells, the invention provides a means to generate and contemporaneously select mutants of interest, allowing for the production of extremely diverse libraries enriched in the most ‘fit’ mutants.