cesium heptafluoroisopropoxide | 13994-52-0

• 分子结构分类: 有机化合物 - 有机盐 - 有机金属盐
• 英文名称: cesium heptafluoroisopropoxide
• 英文别名: Cesium;1,1,1,2,3,3,3-heptafluoropropan-2-olate
• CAS: 13994-52-0
• 化学式: C₃F₇O*Cs
• 分子量: 317.927
• InChiKey: FWSYIBMRSWEHMU-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -1.86
• 重原子数：
  12
• 可旋转键数：
  0
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  23.1
• 氢给体数：
  0
• 氢受体数：
  8

反应信息

• 作为反应物：
  描述：

  cesium heptafluoroisopropoxide 、 2-溴苯乙酮 以 乙二醇二甲醚 为溶剂， 反应 24.0h， 以3.79 g的产率得到phenyl(heptafluoroisopropyloxymethyl)ketone
  参考文献：
  名称：

  Efficient synthesis of 5′-fluoroalkoxythiazoles via α-bromo-α-fluoroalkoxyacetophenones Hantzsch type cyclization with thioureas or thioamides

  摘要：

  Novel alpha-fluoroalkoxyacetophenones were synthesized by addition of the readily available 2,2-dimethoxy-2-phenylethanol to fluoroolefins. alpha-Bromination yielded alpha-bromo-alpha-fluoroalkoxyacetophenones, which on treatment with thioureas or thioamides gave thiazoles with fluoroalkoxy groups at the 5'-position by the Hantzsch-type cyclization. This provides a versatile methodology for the construction of heterocycles from aliphatic fluoroalkoxy containing building blocks. (C) 2012 Elsevier B.V. All rights reserved.

  DOI：

  10.1016/j.jfluchem.2012.01.005
• 作为产物：
  描述：

  六氟丙酮 在 cesium fluoride 作用下， 以 二乙二醇二甲醚 为溶剂， 20.0 ℃ 、100.0 kPa 条件下， 生成 cesium heptafluoroisopropoxide
  参考文献：
  名称：

  헵타플루오로이소프로필옥시 테트라플루오로 프로파노일 플루오라이드의 제조방법

  摘要：

  This text appears to be a technical description related to a patent for a method of producing heptafluoroisopropoxy tetrafluoropropionyl fluoride.

  公开号：

  KR102026794B1

文献信息

• Gubanov, V. A.; Tyul'ga, G. M.; Solodkaya, I. G., Journal of Organic Chemistry USSR (English Translation), 1984, vol. 20, p. 444 - 448
  作者：Gubanov, V. A.、Tyul'ga, G. M.、Solodkaya, I. G.、Sherman, M. A.

  DOI：——

  日期：——
• New Electrophilic Reaction of Perfluoroalkylethylenes. Synthesis and Some Reactions of 1-Halo-1,1,2-trihydroperfluoroalkenes-2
  作者：V. A. Petrov

  DOI：10.1021/jo00116a031

  日期：1995.6

  Perfluoroalkylethylenes, R(f)CH=CH2, react with chlorosulfonic acid in the presence of TaF5 or NbF5 catalyst to form allyl chlorides, Z-R(f)CF=CHCH2Cl. These chlorides, or their corresponding bromides, also can be made by the BF3-catalyzed reaction of R(f)CH=CH2 with HCl or HBr in anhydrous HF. The allylic chlorine in the newly synthesized compounds Z-R(f)CF=CHCH2Cl can be easily replaced by reaction with nucleophiles such as I-, Br-, HO-, or (CF3)(2)CFO-.
• 헵타플루오로이소프로필옥시 테트라플루오로 프로파노일 플루오라이드의 제조방법
  申请人：KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY 한국화학연구원(319980077651)

  公开号：KR102026794B1

  公开（公告）日：2019-09-30

  본 발명은 헵타플루오로이소프로필옥시 테트라플루오로 프로파노일 플루오라이드의 제조방법에 관한 것으로, 본 발명에 따른 헵타플루오로이소프로필옥시 테트라플루오로 프로파노일 플루오라이드 제조방법은, 반응물의 반복적인 교차 투입 방법을 통하여, 생성물로의 전환율을 현저히 향상시키는 유용한 효과가 달성되고, 제조 과정 중에 사용되었던 헵타플루오로아이소프로폭사이드 금속염을 반복 재사용할 수 있는 이점이 있는 바, 연속식 생산 공정이 가능하고, 고순도, 고수율의 헵타플루오로이소프로필옥시 테트라플루오로 프로파노일 플루오라이드 제조가 가능한 유용한 효과가 있다. 또한, 본 발명의 제조방법으로 제조된 헵타플루오로이소프로필옥시 테트라플루오로 프로파노일 플루오라이드는, 말단기를 비닐에테르 또는 에테르로 변환시켜 고분자 중합의 공단량체, 희석제, 세정제 및 코팅제 등으로 제공될 수 있는 바, 유용하다.

  This text appears to be a technical description related to a patent for a method of producing heptafluoroisopropoxy tetrafluoropropionyl fluoride.
• Efficient synthesis of 5′-fluoroalkoxythiazoles via α-bromo-α-fluoroalkoxyacetophenones Hantzsch type cyclization with thioureas or thioamides
  作者：Taras M. Sokolenko、Yulia A. Davydova、Yurii L. Yagupolskii

  DOI：10.1016/j.jfluchem.2012.01.005

  日期：2012.4

  Novel alpha-fluoroalkoxyacetophenones were synthesized by addition of the readily available 2,2-dimethoxy-2-phenylethanol to fluoroolefins. alpha-Bromination yielded alpha-bromo-alpha-fluoroalkoxyacetophenones, which on treatment with thioureas or thioamides gave thiazoles with fluoroalkoxy groups at the 5'-position by the Hantzsch-type cyclization. This provides a versatile methodology for the construction of heterocycles from aliphatic fluoroalkoxy containing building blocks. (C) 2012 Elsevier B.V. All rights reserved.