9,10-dihydro-9,12-diphenyl-8H-benzo[a]xanthen-11(12H)-one | 1372423-88-5

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 新黄酮类化合物
• 英文名称: 9,10-dihydro-9,12-diphenyl-8H-benzo[a]xanthen-11(12H)-one
• 英文别名: 9,12-Diphenyl-8,9,10,12-tetrahydrobenzo[a]xanthen-11-one
• CAS: 1372423-88-5
• 化学式: C₂₉H₂₂O₂
• 分子量: 402.492
• InChiKey: KVTBJNQOXIZDSA-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  6.2
• 重原子数：
  31
• 可旋转键数：
  2
• 环数：
  6.0
• sp3杂化的碳原子比例：
  0.14
• 拓扑面积：
  26.3
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  5-phenyl-cyclohexane-1,3-dione 、 苯甲醛 、 2-萘酚 在 silica sulfuric acid 作用下， 反应 0.58h， 以80%的产率得到9,10-dihydro-9,12-diphenyl-8H-benzo[a]xanthen-11(12H)-one
  参考文献：
  名称：

  用二氧化硅硫酸催化 β-萘酚、芳香醛和环状 1,3-二羰基化合物一锅缩合的高效、无溶剂方法

  摘要：

  摘要 硫酸二氧化硅作为一种可重复使用的高效催化剂，已被用于从芳香醛的一锅多组分反应中制备 12-芳基-8,9,10,12-四氢苯并[a]呫吨-11-酮衍生物。 、β-萘酚和无溶剂条件下的环状二酮。该方法的优点是收率高、程序简单、后处理容易、反应时间短和条件温和。图形概要

  DOI：

  10.1080/00397911.2010.520832

文献信息

• Nano-WO 3 -supported sulfonic acid: New, efficient and high reusable heterogeneous nano catalyst
  作者：Ali Amoozadeh、Salman Rahmani

  DOI：10.1016/j.molcata.2014.09.020

  日期：2015.1

  Nano-WO3-supported sulfonic acid [n-WO3-SO3H (n-WSA)] is easily prepared from the reaction of nano WO3 with chlorosulfonic acid as sulfonating agent. This new catalyst is characterized by X-ray diffraction (XRD), field emission scanning electron microscopy (FE-SEM), FT-IR spectroscopy, thermal gravimetric analysis (TGA), pH analysis and Hammett acidity function. Nano-WO3-supported sulfonic acid is used as an efficient and recyclable catalyst for some organic reactions such as synthesis of 1,8-dioxo-octahydroxanthene, tetrahydrobenzoxanthene and benzimidazolo quinazolinone derivatives. All of the reactions are very fast and the yields are excellent. The used catalyst was easily separated and reused for 10 runs without appreciable loss of its catalytic activity. (C) 2014 Elsevier B.V. All rights reserved.
• Efficient, Solvent-Free Method for the One-Pot Condensation of <font>β</font>-Naphthol, Aromatic Aldehydes, and Cyclic 1,3-Dicarbonyl Compounds Catalyzed by Silica Sulfuric Acid
  作者：Firouzeh Nemati、Maryam Arghan、Ali Amoozadeh

  DOI：10.1080/00397911.2010.520832

  日期：2012.1.1

  reusable and efficient catalyst has been used for the preparation of 12-aryl-8,9,10,12-tetrhydro benzo[a]xanthene-11-one derivatives from the one-pot multicomponent reaction of aromatic aldehydes, β-naphthol, and a cyclic diketone under solvent-free conditions. Good yields, simple procedure, easy workup, short reaction times, and mild conditions are the advantages of this methodology. GRAPHICAL ABSTRACT

  摘要 硫酸二氧化硅作为一种可重复使用的高效催化剂，已被用于从芳香醛的一锅多组分反应中制备 12-芳基-8,9,10,12-四氢苯并[a]呫吨-11-酮衍生物。 、β-萘酚和无溶剂条件下的环状二酮。该方法的优点是收率高、程序简单、后处理容易、反应时间短和条件温和。图形概要