tert-Butyl(dimethyl)silyl undec-10-enoate | 104255-76-7

• 分子结构分类: 有机化合物 - 有机金属化合物 - 有机类金属化合物
• 英文名称: tert-Butyl(dimethyl)silyl undec-10-enoate
• 英文别名: [tert-butyl(dimethyl)silyl] undec-10-enoate
• CAS: 104255-76-7
• 化学式: C₁₇H₃₄O₂Si
• 分子量: 298.541
• InChiKey: UNKQCPOHUHBMPF-UHFFFAOYSA-N

物化性质

• 沸点：
  330.2±21.0 °C(Predicted)
• 密度：
  0.869±0.06 g/cm3(Predicted)
• 保留指数：
  1778.8

计算性质

• 辛醇/水分配系数(LogP)：
  5.84
• 重原子数：
  20
• 可旋转键数：
  12
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.82
• 拓扑面积：
  26.3
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  三乙氧基硅烷 、 tert-Butyl(dimethyl)silyl undec-10-enoate 在 dihydrogen hexachloroplatinate 作用下， 生成 11-(triethoxysilyl)undecanoic acid tert-butyldimethylsilyl ester
  参考文献：
  名称：

  Enhancement of the thermal and storage stability of urease by covalent attachment to phospholipid-bound silica

  摘要：

  Urease was immobilized directly on silanized silica surfaces carrying alkyl moieties with terminal carboxylic groups. The enzyme was also covalently attached to phospholipid-bound silanized silica surfaces through the terminal carboxyl moiety on the sn-2 acyl chain of the lipid. The surfaces were characterized by X-ray photoelectron spectroscopy and ellipsometry. The activity of the immobilized urease was determined by UV spectrophotometry using a urea/bromocresol purple substrate. The enzymic activity decreases exponentially upon storage under dry solid conditions for 1 week or upon heating to 100-degrees-C in the case of the silane/enzyme surfaces. On the other hand, the enzyme immobilized on Phospholipid-carrying silica surfaces retained its entire original activity under dry storage or heat treatment conditions. Such immobilized urease systems could find extensive applicability In the design of in vivo dialysis equipment or for on-line monitoring of urea.

  DOI：

  10.1021/ac00033a018
• 作为产物：
  描述：

  2-十一烯酸 、 叔丁基二甲基氯硅烷 在 咪唑 作用下， 以 N,N-二甲基甲酰胺 为溶剂， 反应 24.0h， 生成 tert-Butyl(dimethyl)silyl undec-10-enoate
  参考文献：
  名称：

  Enhancement of the thermal and storage stability of urease by covalent attachment to phospholipid-bound silica

  摘要：

  Urease was immobilized directly on silanized silica surfaces carrying alkyl moieties with terminal carboxylic groups. The enzyme was also covalently attached to phospholipid-bound silanized silica surfaces through the terminal carboxyl moiety on the sn-2 acyl chain of the lipid. The surfaces were characterized by X-ray photoelectron spectroscopy and ellipsometry. The activity of the immobilized urease was determined by UV spectrophotometry using a urea/bromocresol purple substrate. The enzymic activity decreases exponentially upon storage under dry solid conditions for 1 week or upon heating to 100-degrees-C in the case of the silane/enzyme surfaces. On the other hand, the enzyme immobilized on Phospholipid-carrying silica surfaces retained its entire original activity under dry storage or heat treatment conditions. Such immobilized urease systems could find extensive applicability In the design of in vivo dialysis equipment or for on-line monitoring of urea.

  DOI：

  10.1021/ac00033a018

文献信息

• REACTION OF STABLE TRIALKYLSILYL ESTERS WITH Ph₃P(SCN)₂: A NOVEL METHOD FOR THE PREPARATION OF ACYL AND AROYL ISOTHIOCYANATES UNDER NEUTRAL CONDITION
  作者：N. Iranpoor、H. Firouzabadi、H. R. Shaterian

  DOI：10.1081/scc-120014983

  日期：2002.1

  one-pot conversion of stable triisopropylsilyl- and tert-butyldimethylsilyl carboxylates to their corresponding acyl- or aroyl isothiocyanates using in-situ generation of Ph3P(SCN)2 at room temperature under neutral condition. This method has also been applied for the high yield preparation of 2-thioxo-3,4-dihydro-2H-1,3-benzoxazine-4-one, which has fungicidal and bactericidal activities.

  摘要描述了一种高效、温和且新颖的方法，可在中性条件下在室温下原位生成 Ph3P(SCN)2，将稳定的三异丙基甲硅烷基和叔丁基二甲基甲硅烷基羧酸酯一锅法转化为相应的酰基或芳酰基异硫氰酸酯。该方法还用于高产率制备具有杀菌和杀菌活性的2-thioxo-3,4-dihydro-2H-1,3-benzoxazine-4-one。
• EFFECTIVE SILYLATION OF CARBOXYLIC ACIDS UNDER SOLVENT-FREE CONDITIONS WITH <i>tert</i>-BUTYLDIMETHYLSILYL CHLORIDE (TBDMSCL) AND TRIISOPROPYLSILYL CHLORIDE (TIPSCL)
  作者：Habib Firouzabadi、Naser Iranpoor、Hamid Reza Shaterian

  DOI：10.1080/10426500008076532

  日期：2000.1.1

  Various types of carboxylic acids can be converted effectively to their corresponding TBDMS and TIPS esters using TBDMSCI and TIPSCI in the presence of imidazole under solvent-free conditions. The advantage of this modified method in comparison with that reported by Corey is the elimination of DMF, which eliminates aqueous work-up. The method is not a time-consuming process and the reactions proceed spontaneously. By this method, absolute chemoselectivity for the protection of carboxylic acid functions in the presence of 2 degrees, 3 degrees hydroxyl groups are observed.