vinyl stannane | 53593-61-6

• 分子结构分类: 有机化合物 - 有机金属化合物 - 有机过渡后金属化合物
• 英文名称: vinyl stannane
• 英文别名: Z-vinylstannane；Vinylstannane；ethenylstannane
• CAS: 53593-61-6
• 化学式: C₂H₆Sn
• 分子量: 148.78
• InChiKey: BADWIIDKTXQYLW-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -0.5
• 重原子数：
  3
• 可旋转键数：
  0
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  0
• 氢给体数：
  0
• 氢受体数：
  0

反应信息

• 作为反应物：
  描述：

  vinyl stannane 生成 (1R,2R,E)-1-((2R,3R)-3-((2R,3S)-3-methoxypentan-2-yl)oxiran-2-yl)-2-methyl-4-(tributylstannyl)but-3-en-1-ol
  参考文献：
  名称：

  ANTICANCER AND ANTIFUNGAL SPLICE MODULATORS

  摘要：

  本文提供了剪接调节化合物，其中包括FD-895的光学纯、立体特异性类似物。本文提供的方法允许例如可扩展制备所述化合物，并进一步允许例如使用所述化合物抑制剪接体活性。

  公开号：

  US20220227742A1
• 作为产物：
  描述：

  alkaline earth salt of/the/ methylsulfuric acid 在 lithium aluminium tetrahydride 、 二乙二醇二甲醚 作用下， 生成 vinyl stannane
  参考文献：
  名称：

  乙烯基锗烷：制备和聚合

  摘要：

  用氢化铝锂还原乙烯基三氯锗烷产生乙烯基锗烷[bp -3·5°（萃取）]，该化合物在日光下聚合成白色固体，尤其是在汞存在下。聚合的乙烯基锗烷在275°以上开始可测量的分解，产生的氢气中乙烯和锗烷的含量较少。像聚合乙烯基硅烷一样，聚乙烯锗烷不溶于多种溶剂。两种聚合物的红外光谱彼此相似，并且两种可能具有相似的结构。正如预期的那样，发现锡酸乙烯酯的稳定性要比乙烯基锗烷低得多，锡化合物只能以极少量的量制备，并且必须在低温下保存以避免分解。一个似乎涉及多个途径的过程。

  DOI：

  10.1016/0022-1902(59)80211-6
• 作为试剂：
  描述：

  trans-1-Tributylstannyl-3-trimethylsilyloxy-1-octene 、 甲基二苯基膦硫化物 在 Bu₃ P 正丁基锂 、 乙烯基-锂 、 vinyl stannane 作用下， 以 四氢呋喃 、 乙醚 为溶剂， 以67%的产率得到6-(3-Hydroxy-(1E)-octenyl)-2,2-dimethyl-3aβ,5,6α,6aβ-tetrahydro-4H-cyclopenta-1,3-dioxol-4-one
  参考文献：
  名称：

  Process for the preparation of cyclopentanoids and novel intermediates

  摘要：

  描述了公式为：##STR1##的环戊烷酮(I)，包括立体异构体，以及制备I的过程。特别描述了公式为：##STR2##的前列腺素的制备，其中R.sub.1是含有1到8个碳原子的烷基基团，R.sub.2 CO.sub.2 R.sub.3是烯基酯基团，R.sub.2含有2到6个碳原子，R.sub.3是含有1到6个碳原子的低烷基基团。该过程制备的特定前列腺素是PGE.sub.2。已经证明这些前列腺素在动物和人体中具有药理活性。还描述了(I)的新颖中间体。

  公开号：

  US04873360A1

文献信息

• Angiotensin II receptor blocking 2,3,6-substituted quinazolinones
  申请人：American Cyanamid Company

  公开号：US05284852A1

  公开（公告）日：1994-02-08

  This disclosure describes novel 2,3,6-substituted quinazolinones having the formula: ##STR1## wherein R.sup.6, X and R are as described in the specification which have activity as angiotensin II (AII) antagonists.

  本公开描述了具有以下式子的新型2,3,6-取代喹唑啉酮：##STR1## 其中R.sup.6、X和R如规范中描述的具有作为血管紧张素II（AII）拮抗剂的活性。
• Gmelin Handbuch der Anorganischen Chemie, Gmelin Handbook: Sn: Org.Verb.4, 1.2.3.3, page 125 - 128
  作者：

  DOI：——

  日期：——
• Vinylstannanes: synthesis and characterization
  作者：Tajdine Janati、Jean-Claude Guillemin、Mohammed Soufiaoui

  DOI：10.1016/0022-328x(94)05057-i

  日期：1995.1

  Primary, secondary and tertiary vinylstannanes 2a-2f are synthesized by reduction of the corresponding chloro(vinyl)stannanes. They are characterized by their spectral data (IR, NMR (Sn-119, C-13, H-1) spectroscopy and mass spectrometry). The Sn-119 chemical shifts and (1)J(SnH) and (1)J(SnC) of vinylstannanes are compared with the data reported for the corresponding alkyl- and aryl-stannanes. Compounds 2 decompose slowly at room temperature in benzene (tau(1/2) 1-3 days). The formation of divinylchlorostannane and the use of trivinylstannane as a reducing agent are also reported.
• Structures of Vinylstannane (Ethenylstannane) and Allylstannane (2-Propenylstannane) Determined by Gas-Phase Electron Diffraction and Quantum Chemical Calculations
  作者：Tatyana Strenalyuk、Svein Samdal、Harald Møllendal、Jean-Claude Guillemin

  DOI：10.1021/om0601549

  日期：2006.5.1

  Vinylstannane (H2C=CHSnH3) and allylstannane (H2C=CHCH2SnH3) have been synthesized, and their structures and conformational properties have been determined by A initio and density functional theory calculations and gas electron diffraction. There is only one stable conformation of vinylstannane, where one of the Sn-H bonds is synperiplanar to the double bond. The most important structural parameter is the C(sp(2))-Sn(IV) bond length, which is r(a) = 215.1(6) pm (r(c) = 214.1(6) pm). The CCSn bond angle is 121.6(4)degrees. Uncertainties are estimated errors equal to 2.5 times the least-squares standard deviation and include uncertainty in the electron wavelength. Theoretical calculations indicate that there are two stable rotameric forms of allystannane. The C=C-C-Sn chain of atoms is synperiplanar (dihedral angle = 0 degrees) in the less stable form and anticlinal (dihedral angle approximate to 106 degrees from synperiplanar) in the more stable rotamer. Theoretical calculations predict an energy difference between the two conformations of about 10 kJ mol(-1). There is no indication of the presence of the synperiplanar conformation in the gas phase at room temperature. The final analysis was therefore carried out assuming that only the anticlinal conformer was present. The C=C-C-Sn dihedral angle was found to be 102.9(19)degrees from the synperiplanar conformer, which is the smallest value found for this angle in the C=C-C-X (X = C, Si, Ge, Sn) series of compounds. The C(sp(3)) -Sn(IV) bond length is r(a) = 218.9(8) pm (r(e) = 217.6(8) pm), and the CCSn bond angle is 110.9(6)degrees. The B3LYP calculations using the cc-pVTZ basis set for C and H and the cc-pVTZ-PP basis set for Sri reproduce the experimental r(e)(C-Sn) bond distances very well, while the MP2(FC) calculations underestimate the r(e)(C-Sn) bond distances by 3-4 pm.
• WO2006/51394
  申请人：——

  公开号：——

  公开（公告）日：——