1-undecyl-3-[(1R,2R)-2-(undecylcarbamoylamino)cyclohexyl]urea | 328092-10-0

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 有机碳酸及其衍生物
• 英文名称: 1-undecyl-3-[(1R,2R)-2-(undecylcarbamoylamino)cyclohexyl]urea
• CAS: 328092-10-0
• 化学式: C₃₀H₆₀N₄O₂
• 分子量: 508.832
• InChiKey: CYLINPDAWYSDIT-VSGBNLITSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  9.9
• 重原子数：
  36
• 可旋转键数：
  22
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.93
• 拓扑面积：
  82.3
• 氢给体数：
  4
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  十二烷基异氰酸酯 、 (1R,2R)-1,2-diaminocyclohexane 以 乙醚 、 二氯甲烷 、 甲苯 为溶剂， 生成 1-undecyl-3-[(1R,2R)-2-(undecylcarbamoylamino)cyclohexyl]urea
  参考文献：
  名称：

  二氧化硅纳米管内外表面的化学功能截然不同及其在多种化学传感器中的应用

  摘要：

  内外：二氧化硅纳米管（SNT）的内外表面可以通过溶胶-凝胶接枝反应进行独立修饰。外表面的基于偶氮苯的配体通过颜色变化识别Hg 2+，而内表面的基于BODIPY的配体通过荧光增强识别Pb 2+。因此，修饰的SNT选择性地识别Hg 2+和Pb 2+（见图）。

  DOI：

  10.1002/chem.201100011

文献信息

• Thymidine-functionalized silica nanotubes for selective recognition and separation of oligoadenosines
  作者：Nam Hoon Kim、Hye Young Lee、Youngje Cho、Won Seok Han、Dongmin Kang、Shim Sung Lee、Jong Hwa Jung

  DOI：10.1039/b923029g

  日期：——

  Thymidine receptor residues were covalently attached to the inner side wall of silica nanotubes (SNTs). The adsorption capacities of the thymidine-functionalized silica nanotubes (T-SNTs) with nucleic acids and oligonucleic acids were evaluated. The T-SNTs exhibited excellent selectivity both in recognition and separation of adenosine and adenosine-based oligonucleotides, because adenosine and oligoadenosine were selectively bound to the inner surface of T-SNTs by formation of complementary intermolecular hydrogen bonds. On the other hand, guanosine, cytosine and oligoguanosine derivatives were not bound to the T-SNTs. The T-SNTs selectively separated 95% of oligoadenosine from a mixture of equal amounts of oligocytosine and oligoguanosine. Our results imply that the T-SNTs can be used as a selective receptor and separator for the extraction and separation of adenosine and oligoadenosine derivatives in aqueous solution.

  胸苷受体残基以共价方式固定在硅纳米管（SNTs）的内侧壁上。评估了胸苷功能化硅纳米管（T-SNTs）与核酸和寡核苷酸的吸附能力。T-SNTs在识别和分离腺苷及腺苷基寡核苷酸方面表现出优异的选择性，因为腺苷和寡腺苷通过形成互补的分子间氢键，选择性地结合在T-SNTs的内表面上。另一方面，鸟苷、胞苷和寡鸟苷衍生物未能与T-SNTs结合。T-SNTs能够从等量的寡胞苷和寡鸟苷的混合物中选择性分离出95%的寡腺苷。我们的结果表明，T-SNTs可以作为选择性受体和分离剂，用于在水溶液中提取和分离腺苷及寡腺苷衍生物。
• Solution casting method and polymer film
  申请人：Sugiura Masaru

  公开号：US20050077648A1

  公开（公告）日：2005-04-14

  A solvent in which dichloromethane is mixed with alcohol as a poor solvent is used for preparing a dope. Alcohol is supplied to the dope in a inline pipe to mix with a static mixer, such as a casting dope in which a composition of alcohol is increased. The temperature of the rotary drum is adjusted to −7° C. The casting dope is fed from a casting die to the rotary drum so as to form a casting film whose thickness is 40 μm. Since the content of alcohol is high and a storage modulus of the cooled casting film is at least 150 thousands Pa, the peeling defect does not occur, and the stretch is reduced as far as possible. A gel-like film is dried by a tenter type drying device, and stretched such that the stretch ratio is at most 110%. The produced film is thin and excellent in a surface condition and optical isotropy.

  二氯甲烷与作为劣质溶剂的酒精混合的溶剂用于制备涂料。酒精通过内联管道供应到涂料中，与静态混合器混合，如增加酒精成分的铸造涂料。将浇注料从浇注模具送入旋转滚筒，以形成厚度为 40 μm 的浇注膜。由于酒精含量高，冷却后的浇注膜的储存模量至少为 15 万帕，因此不会出现剥离缺陷，拉伸也尽可能减小。凝胶状薄膜由拉幅机干燥，拉伸率不超过 110%。生产出的薄膜很薄，表面状态和光学各向同性都很好。
• Distinctly Different Chemical Functionalities on the Internal and the External Surfaces of Silica Nanotubes, and Their Applications as Multi-Chemosensors
  作者：Sungmin Seo、Ji Ha Lee、Youngje Cho、Jin-Gyu Kim、Changyeon Kim、Jong Hwa Jung

  DOI：10.1002/chem.201100011

  日期：2011.6.27

  Inside and out: The external and internal surface of silica nanotubes (SNTs) can be independently modified by a sol–gel grafting reaction. The azobenzene‐based ligands on the external surface recognize Hg2+ through a color change, whereas the BODIPY‐based ligands attached to the internal surface recognize Pb2+ through fluorescence enhancement. Thus, the modified SNTs selectively recognize both Hg2+

  内外：二氧化硅纳米管（SNT）的内外表面可以通过溶胶-凝胶接枝反应进行独立修饰。外表面的基于偶氮苯的配体通过颜色变化识别Hg 2+，而内表面的基于BODIPY的配体通过荧光增强识别Pb 2+。因此，修饰的SNT选择性地识别Hg 2+和Pb 2+（见图）。