(1-methylethyl)-phosphoramidochloridothioic acid, O-ethyl-ester | 690-74-4

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 有机硫代磷酸及其衍生物
• 英文名称: (1-methylethyl)-phosphoramidochloridothioic acid, O-ethyl-ester
• 英文别名: O-ethyl N-isopropylphosphoramidochloridothionate；O-ethyl N-isopropyl-chlorothiophosphoramidate；N-[chloro(ethoxy)phosphinothioyl]propan-2-amine
• CAS: 690-74-4
• 化学式: C₅H₁₃ClNOPS
• 分子量: 201.657
• InChiKey: VGSMIMPEXGGDLP-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.9
• 重原子数：
  10
• 可旋转键数：
  4
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  53.4
• 氢给体数：
  1
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  (1-methylethyl)-phosphoramidochloridothioic acid, O-ethyl-ester 在 氢氧化钾 作用下， 以 乙醇 为溶剂， 生成 Thiophosphorsaeure-ethylester-isopropylamid
  参考文献：
  名称：

  Mandel'baum,Ya.A. et al., Journal of general chemistry of the USSR, 1968, vol. 38, p. 1712 - 1713

  摘要：

  DOI：

文献信息

• Triazinyl-organophosphorus esters
  申请人：Sumitomo Chemical Company, Limited

  公开号：US04320126A1

  公开（公告）日：1982-03-16

  Organophosphorus esters of the formula (I), ##STR1## wherein R is a C.sub.1 -C.sub.2 alkyl group, R.sub.1 is a C.sub.1 -C.sub.2 alkyl, C.sub.1 -C.sub.2 alkoxy, C.sub.1 -C.sub.4 alkylamino, phenyl or phenoxy group, R.sub.2 and R.sub.3, which may be the same or different, are each a C.sub.1 -C.sub.5 alkyl or methoxy C.sub.2 -C.sub.3 alkyl group and X is an oxygen or sulfur atom, a method for producing organophosphorus esters of the formula (I) characterized by condensation reaction of s-triazines of the formula, ##STR2## wherein M is a potassium or sodium atom and R.sub.2 and R.sub.3 are as defined above, with a halogenated compound of the formula, ##STR3## wherein Y is a halogen atom and R, R.sub.1 and X are as defined above, and an insecticide, acaricide and/or nematocide characterized by containing organophosphorus esters of the formula (I) as an active ingredient.

  式(I)的有机磷酸酯，其中R是C.sub.1-C.sub.2烷基，R.sub.1是C.sub.1-C.sub.2烷基，C.sub.1-C.sub.2烷氧基，C.sub.1-C.sub.4烷基氨基，苯基或苯氧基，R.sub.2和R.sub.3，可以相同也可以不同，分别是C.sub.1-C.sub.5烷基或甲氧基C.sub.2-C.sub.3烷基，X是氧或硫原子，一种制备式(I)的有机磷酸酯的方法，其特征在于将式中的s-三嗪化合物与式中的卤代化合物进行缩合反应，其中M是钾或钠原子，R.sub.2和R.sub.3如上所定义，Y是卤素原子，R，R.sub.1和X如上所定义，以及一种杀虫剂，杀螨剂和/或杀线虫剂，其特征在于含有式(I)的有机磷酸酯作为活性成分。
• Phosphoramidothionate, and their production and use
  申请人：SUMITOMO CHEMICAL COMPANY, LIMITED

  公开号：EP0096993A2

  公开（公告）日：1983-12-28

  A compound of the formula: wherein R, is a hydrogen atom, a lower alkyl group, a lower alkenyl group, a lower alkylnyl group, a lower cycloalkyl group, a lower cycloalkyl(lower)alkyl group, a halo(lower)-alkyl group, a lower alkoxy(lower)alkyl group, a di(lower)-alkoxy(lower)alkyl group, a cyano(lower)alkyl group, a lower alkylthio(lower)alkyl group, a lower alkynylthio(lower)alkyl group, a lower dioxothiacycloalkyl group, a lower thiacycloalkyl group, a lower oxacycloalkyl group, a lower oxacycloalkyl(lower)alkyl group or a thienyl(lower)alkyl group, R2 is a lower alkyl group and R3 is a 3,5-dimethoxyphenyl group, a 3,4-methylenedioxyphenyl group or a 4,5-methylenedioxy-2-nitrophenyl group, which is useful as a fungicide.

  式中的化合物： 其中 R 是氢原子、低级烷基、低级烯基、低级炔基、低级环烷基、低级环烷基（低级）烷基、卤代（低级）烷基、低级烷氧基（低级）烷基、二（低级）烷氧基（低级）烷基、氰基（低级）烷基、低级烷硫基（低级）烷基、低级炔硫基（低级）烷基、R2为低级烷基，R3为 3,5-二甲氧基苯基、3,4-亚甲二氧基苯基或 4,5-亚甲二氧基-2-硝基苯基，可用作杀真菌剂。
• Method and composition for enhancing the insecticidal activity of certain organophosphorus compounds
  申请人：THE DOW CHEMICAL COMPANY

  公开号：EP0185778A1

  公开（公告）日：1986-07-02

  The insecticidal activity of certain pyridinyl phosphorous compounds corresponding to wherein each X independently represents bromo, chloro, fluoro or iodo; Z represents oxygen or sulfur; each R independently represents alkoxy of 1 to 4 carbon atoms and n represents an integer of from 1 to 3 is enhanced by the admixture therewith of certain 2,5,6-trisubstituted-4-pyrimidinyl phosphoramidates or phosphoramidothioates corresponding to the formula wherein A represents hydrogen, alkyl of 1 to 4 carbon atoms, alkylthio of 1 to 4 carbon atoms, allylthio, cycloalkyl of 3 or 4 carbon atoms, alkyl(cycloalkyl) wherein the alkyl group is of 1 to 4 carbon atoms and the cycloalkyl group is of 3 or 4 carbon atoms, (cycloalkyl)alkyl wherein the alkyl group is of 1 to 4 carbon atoms and the cycloalkyl group is of 3 or 4 carbon atoms, phenyl, trifluoromethyl, dialkylamino wherein each alkyl group is independently of 1 to 4 carbon atoms or morpholino; R represents hydrogen, chloro, trifluoromethyl, alkyl of 1 to 4 carbon atoms or alkylthio of 1 to 4 carbon atoms (alkylthio)alkyl wherein each alkyl group is independently of 1 to 4 carbon atoms, alkoxyalkyl wherein the alkoxy and alkyl groups are independently of 1 to 4 carbon atoms, cycloalkyl of 3 or 4 carbon atoms or a group of the formula R represents alkyl of 1 to 4 carbon atoms; R2 represents monoalkylamino of 1 to 4 carbon atoms, dialkylamino wherein each alkyl group is independently of 1 to 4 carbon atoms, allylamino, ((dimethylamino)methylene)amino (-N-=CH-N(CH3)2 or monocycloalkylamino of 3 to 4 carbon atoms; R3 represents hydrogen, chloro, bromo, fluoro or methyl and Z is oxygen or sulfur.

  某些吡啶磷化合物的杀虫活性相当于 其中每个 X 独立地代表溴、氯、氟或碘；Z 代表氧或硫；每个 R 独立地代表 1 至 4 个碳原子的烷氧基和 n 代表 1 至 3 的整数，掺入某些 2,5,6-三取代-4-嘧啶基磷酰胺酸盐或硫代磷酰胺酸盐可增强其杀虫活性，这些磷酰胺酸盐或硫代磷酰胺酸盐的化学式如下 其中 A 代表氢、1 至 4 个碳原子的烷基、1 至 4 个碳原子的烷硫基、烯丙基硫代、3 或 4 个碳原子的环烷基、烷基（环烷基）（其中烷基为 1 至 4 个碳原子，环烷基为 3 或 4 个碳原子）、（环烷基）烷基（其中烷基为 1 至 4 个碳原子，环烷基为 3 或 4 个碳原子）、苯基、三氟甲基、二烷基氨基（其中每个烷基独立地为 1 至 4 个碳原子）或吗啉基；R 代表氢、氯、三氟甲基、1 至 4 个碳原子的烷基或 1 至 4 个碳原子的烷硫基 （其中每个烷基独立地为 1 至 4 个碳原子）、烷氧基烷基（其中烷氧基和烷基独立地 为 1 至 4 个碳原子）、3 或 4 个碳原子的环烷基或式中的一个基团。 R 代表 1 至 4 个碳原子的烷基；R2 代表 1 至 4 个碳原子的单烷基氨基、二烷基氨基（其中每个烷基独立为 1 至 4 个碳原子）、烯丙基氨基、（（二甲基氨基）亚甲基）氨基（-N-=CH-N(CH3)2 或 3 至 4 个碳原子的单环烷基氨基）；R3 代表氢、氯、溴、氟或甲基，Z 代表氧或硫。
• DE2212906
  申请人：——

  公开号：——

  公开（公告）日：——
• Lysak, E. I.; Rymareva, T. G.; Khaskin, B. A., Journal of general chemistry of the USSR, 1992, vol. 62, # 8.1, p. 1463 - 1466
  作者：Lysak, E. I.、Rymareva, T. G.、Khaskin, B. A.

  DOI：——

  日期：——