(E)-N-[2-(4-methylstyryl)benzyl]aniline | 1262589-64-9

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 二苯乙烯类
• 英文名称: (E)-N-[2-(4-methylstyryl)benzyl]aniline
• 英文别名: N-[[2-[(E)-2-(4-methylphenyl)ethenyl]phenyl]methyl]aniline
• CAS: 1262589-64-9
• 化学式: C₂₂H₂₁N
• 分子量: 299.415
• InChiKey: UNPAAOCQHGUOFY-FOCLMDBBSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  6
• 重原子数：
  23
• 可旋转键数：
  5
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.09
• 拓扑面积：
  12
• 氢给体数：
  1
• 氢受体数：
  1

反应信息

• 作为产物：
  描述：

  Alpha-甲基苯乙烯 、 N-苄叉苯胺 在 [HRe(CO)4]n 作用下， 以 甲苯 为溶剂， 反应 24.0h， 以90%的产率得到(E)-N-[2-(4-methylstyryl)benzyl]aniline
  参考文献：
  名称：

  Rhenium-catalyzed insertion of terminal alkenes into a C(sp2)–H bond and successive transfer hydrogenation

  摘要：

  Treatment of aromatic aldimines with terminal alkenes in the presence of a rhenium catalyst, [HRe(CO)(4)](n), gives 2-alkenylbenzylamines in good to excellent yields. This reaction proceeds via the insertion of the alkene into a C-H bond at the ortho-position of the imino group of the aromatic aldimine followed by sequential beta-hydride elimination from the formed alkyl rhenium intermediate and then by hydrogenation of the imino group of the aldimine. (C) 2010 Elsevier B.V. All rights reserved.

  DOI：

  10.1016/j.jorganchem.2010.09.064

文献信息

• Rhenium-catalyzed insertion of terminal alkenes into a C(sp2)–H bond and successive transfer hydrogenation
  作者：Yoichiro Kuninobu、Takahiro Nakahara、Peng Yu、Kazuhiko Takai

  DOI：10.1016/j.jorganchem.2010.09.064

  日期：2011.1

  Treatment of aromatic aldimines with terminal alkenes in the presence of a rhenium catalyst, [HRe(CO)(4)](n), gives 2-alkenylbenzylamines in good to excellent yields. This reaction proceeds via the insertion of the alkene into a C-H bond at the ortho-position of the imino group of the aromatic aldimine followed by sequential beta-hydride elimination from the formed alkyl rhenium intermediate and then by hydrogenation of the imino group of the aldimine. (C) 2010 Elsevier B.V. All rights reserved.