Disodium 5-amino-2-[2-(4-nitro-2-sulphonatophenyl)vinyl]benzenesulphonate | 6634-82-8

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 二苯乙烯类
• 英文名称: Disodium 5-amino-2-[2-(4-nitro-2-sulphonatophenyl)vinyl]benzenesulphonate
• 英文别名: disodium;5-amino-2-[(E)-2-(4-nitro-2-sulfonatophenyl)ethenyl]benzenesulfonate
• CAS: 6634-82-8；84787-94-0
• 化学式: C14H10N2Na2O8S2
• 分子量: 444.4
• InChiKey: RXYPPHDUSQFWID-SEPHDYHBSA-L

计算性质

• 辛醇/水分配系数(LogP)：
  -4.84
• 重原子数：
  28
• 可旋转键数：
  4
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  203
• 氢给体数：
  1
• 氢受体数：
  9

文献信息

• Water soluble disazo compound, copper salt thereof, and sheet or film colored therewith
  申请人：NIPPON KAYAKU KABUSHIKI KAISHA

  公开号：EP0160113A1

  公开（公告）日：1985-11-06

  A water soluble disazo compound represented by the general formula: wherein X represents a hydrogen atom or a methyl, methoxy or ethoxy group, Y represents a methoxy or ethoxy group, R1 represents a hydrogen atom or a methyl group, R2 represents a hydrogen atom or a methyl, -C2H40H, group,and the group is bonded at the 6- or 7- position, a copper complex salt thereof, and a sheet or film coloured therewith.

  一种由通式表示的水溶性二氮杂化合物，其中 X 代表氢原子或甲基、甲氧基或乙氧基，Y 代表甲氧基或乙氧基，R1 代表氢原子或甲基，R2 代表氢原子或甲基，-C2H40H，且该基团键合在 6- 或 7- 位上；一种铜络合盐；以及用其着色的片材或薄膜。
• METHOD OF ASSAY WITH SULFONIC ACID COMPOUND AND NITRO COMPOUND
  申请人：ARKRAY, Inc.

  公开号：EP1515144A1

  公开（公告）日：2005-03-16

  A method for measuring an analyte in a sample by using a redox reaction is provided, which gives values with excellent reliability. Prior to the redox reaction, at least one of a sulfonic acid compound and a nitro compound is added to the sample to eliminate the influence of hemoglobin and any hemoglobin degradation products as reducing substances contained in the sample. Subsequently, a reducing or oxidizing substance derived from the analyte is caused to generate, and the amount thereof is measured by the redox reaction. The amount of the analyte is determined from the measurement value. The sulfonic acid compound may be sodium lauryl sulfate, and the nitro compound may be 4-nitrophenol, etc.

  本发明提供了一种利用氧化还原反应测量样品中分析物的方法，其测量值非常可靠。在进行氧化还原反应之前，先将磺酸化合物和硝基化合物中的至少一种添加到样品中，以消除样品中含有的血红蛋白和任何血红蛋白降解产物作为还原性物质的影响。随后，使分析物产生还原性或氧化性物质，并通过氧化还原反应测量其含量。根据测量值确定被分析物的量。磺酸化合物可以是十二烷基硫酸钠，硝基化合物可以是 4-硝基苯酚等。
• METHOD OF DECOMPOSING PROTEIN WITH SULFONIC ACID COMPOUND
  申请人：ARKRAY, Inc.

  公开号：EP1522593A1

  公开（公告）日：2005-04-13

  A method of assaying a glycated protein in a sample with the use of redox reaction, in which highly reliable measurement can be obtained. A sample containing a glycated protein is treated with protease in the presence of a sulfonic acid compound, so that the glycated protein is degraded. The glycated portion of the resultant glycated protein degradation product is reacted with fructosyl amino acid oxidase, and this redox reaction is measured, thereby determining the amount of glycated protein. Sodium lauryl sulfate can be used as the sulfonic acid compound.

  一种利用氧化还原反应检测样品中糖化蛋白质的方法，可获得高度可靠的测量结果。在磺酸化合物存在的情况下，用蛋白酶处理含有糖化蛋白质的样品，使糖化蛋白质降解。糖化蛋白质降解产物中的糖化部分与果糖基氨基酸氧化酶发生反应，然后对这种氧化还原反应进行测量，从而确定糖化蛋白质的量。十二烷基硫酸钠可用作磺酸化合物。
• METHOD FOR MEASURING GLYCATION RATE OF HEMOGLOBIN
  申请人：TOYOBO CO., LTD.

  公开号：EP3550030A1

  公开（公告）日：2019-10-09

  The present invention provides a method for measuring a glycated hemoglobin ratio, the method comprising bringing a sample containing glycated hemoglobin into contact with a compound having a sulfo group; allowing glycated amino acid oxidase to act on the sample containing glycated hemoglobin to produce hydrogen peroxide; bringing the hydrogen peroxide produced in the above step into contact with a chromogenic substrate in the presence of peroxidase to produce a color-forming dye; measuring the amount of coloring of the color-forming dye obtained in the above step; and applying the amount of coloring obtained in the above step to a calibration curve of a glycated hemoglobin ratio and the amount of coloring previously created using one or more glycated hemoglobin calibrators value-assigned by one or more glycated hemoglobin ratios to determine a glycated hemoglobin ratio.

  本发明提供了一种测量糖化血红蛋白比率的方法，该方法包括：使含有糖化血红蛋白的样品与具有磺基的化合物接触；使糖化氨基酸氧化酶作用于含有糖化血红蛋白的样品，产生过氧化氢；在过氧化物酶存在下，使上述步骤中产生的过氧化氢与发色基质接触，产生发色染料；测量上述步骤中获得的成色染料的着色量；将上述步骤中获得的着色量应用于糖化血红蛋白比率的校准曲线和先前使用一个或多个糖化血红蛋白校准物值分配的糖化血红蛋白比率的着色量，以确定糖化血红蛋白比率。
• RADICAL-GENERATING CATALYST, RADICAL PRODUCTION METHOD, OXIDATION REACTION PRODUCT PRODUCTION METHOD, CHEMICAL AGENT, AND CHEMICAL AGENT FOR AGRICULTURE AND LIVESTOCK
  申请人：Acenet Inc.

  公开号：EP3626339A1

  公开（公告）日：2020-03-25

  The present invention is intended to provide a radical generating catalyst that can generate (produce) radicals under mild conditions. In order to achieve the above object, the first radical generating catalyst of the present invention includes: at least one selected from the group consisting of amino acids, peptides, phospholipids, and salts thereof. The second or third radical generating catalyst of the present invention includes an ammonium salt represented by the following chemical formula (XI) (excluding peroxodisulfate) and having a Lewis acidity of 0.4 eV or more. In the chemical formula (XI), R11, R21, R31, and R41 are each a hydrogen atom or an aromatic ring, or an alkyl group, the alkyl group may include an ether bond, a carbonyl group, an ester bond, or an amide bond, or an aromatic ring, and R11, R21, R31, and R41 may be identical to or different from each other; or two or more of R11, R21, R31, and R41 may be integrated to form a ring structure with N+ to which they are bonded, and the ring structure may be saturated or unsaturated, aromatic or non-aromatic, and may or may not have one or more substituents. X- is an anion (excluding peroxodisulfate ion).

  本发明旨在提供一种能在温和条件下生成（产生）自由基的自由基生成催化剂。为了实现上述目的，本发明的第一种自由基生成催化剂包括：至少一种选自氨基酸、肽、磷脂及其盐组成的组。本发明的第二或第三自由基生成催化剂包括由以下化学式（XI）代表的铵盐（不包括过二硫酸盐），其路易斯酸度为 0.4 eV 或以上。 在化学式（XI）中，R11、R21、R31 和 R41 各为氢原子或芳香环，或烷基，烷基可包括醚键、羰基、酯键或酰胺键，或芳香环，R11、R21、R31 和 R41 可彼此相同或不同；或两个或两个以上的 R11、R21、R31 和 R41 可与它们所键合的 N+ 整合形成环结构，该环结构可以是饱和或不饱和的，芳香或非芳香的，可以有或没有一个或多个取代基。X- 是阴离子（不包括过二硫酸根离子）。