1-Methyl-3,4-diphenyl-piperidin-4-ol | 13427-24-2

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 二苯乙烯类
• 英文名称: 1-Methyl-3,4-diphenyl-piperidin-4-ol
• 英文别名: 1-Methyl-3,4-diphenylpiperidin-4-ol
• CAS: 13427-24-2
• 化学式: C₁₈H₂₁NO
• 分子量: 267.371
• InChiKey: CHRSBWPLDAJHHB-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.8
• 重原子数：
  20
• 可旋转键数：
  2
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.33
• 拓扑面积：
  23.5
• 氢给体数：
  1
• 氢受体数：
  2

文献信息

• STABLE FORMULATIONS OF A HYALURONAN-DEGRADING ENZYME
  申请人：Halozyme, Inc.

  公开号：EP2720712A2

  公开（公告）日：2014-04-23
• CONTINUOUS SUBCUTANEOUS INSULIN INFUSION METHODS WITH A HYALURONAN DEGRADING ENZYME
  申请人：Halozyme, Inc.

  公开号：EP2720713A2

  公开（公告）日：2014-04-23
• Stable formulations of a hyaluronan-degrading enzyme
  申请人：Yang Tzung-Horng

  公开号：US20130011378A1

  公开（公告）日：2013-01-10

  Provided are compositions that are stable formulations of a hyaluronan-degrading enzyme or are stable co-formulations of a fast-acting insulin and a hyaluronan degrading enzyme, including a recombinant human PH20 (rHuPH20).
• Stable formulations of a hyaluronan-degrading enzyme related applications
  申请人：Yang Tzung-Horng

  公开号：US20130022588A1

  公开（公告）日：2013-01-24

  Provided are compositions that are stable formulations of a hyaluronan-degrading enzyme or are stable co-formulations of a fast-acting insulin and a hyaluronan degrading enzyme, including a recombinant human PH20 (rHuPH20).
• Continuous subcutaneous insulin infusion methods with a hyaluronan-degrading enzyme
  申请人：Vaughn Daniel Edward

  公开号：US20130022592A1

  公开（公告）日：2013-01-24

  Provided are methods for continuous subcutaneous insulin infusion (CSII) that employ a hyaluronan-degrading enzyme, including a recombinant human PH20 (rHuPH20). The methods can be used to more consistently control blood glucose during the course of CSII. The methods can be used to treat subjects having diabetes or other insulin-associated disease or condition.