1,2-Bis(naphthalen-1-ylmethylideneamino)guanidine

• 分子结构分类: 有机化合物 - 苯类化合物 - 萘
• 英文名称: 1,2-Bis(naphthalen-1-ylmethylideneamino)guanidine
• 英文别名: 1,2-bis(naphthalen-1-ylmethylideneamino)guanidine
• 化学式: C₂₃H₁₉N₅
• 分子量: 365.437
• InChiKey: DSIMGAKNHDMJLZ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5
• 重原子数：
  28
• 可旋转键数：
  5
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  75.1
• 氢给体数：
  2
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  4-喹啉甲醛 、 1,3-二氨基胍盐酸盐 以 甲醇 为溶剂， 反应 6.0h， 以86%的产率得到1,2-Bis(naphthalen-1-ylmethylideneamino)guanidine
  参考文献：
  名称：

  A guanidine based bis Schiff base chemosensor for colorimetric detection of Hg(II) and fluorescent detection of Zn(II) ions

  摘要：

  A novel guanidine base colorimetric and fluorescent bis Schiff base chemosensor L has been designed synthesized and characterized by elemental analyses,H-1 NMR, FT-IR and ESI-MS spectral analysis. The chemosensor L could detect Hg2+ by "naked eye" colour change from yellow to red and Zn2+ through selective fluorescence enhancement in CH3OH-tris buffer (1/1, v/v) over other metal ions commonly obtained in physiological and environmental samples. The Job's plot analysis revealed that 1:2 and 1:1 coordination patterns for L-Hg2+ and LZn2+ complexes respectively, which have further been confirmed by ESI-MS spectra. The DFT calculations are also in agreement with the experimental results. The limit of detection for Hg2+ and Zn2+ are found to be 9.89 x 10(-7) M and 1.23 x 10(-6) M respectively, which are far below than the guidelines provided by World Health Organization (WHO) for drinking water. Moreover the chemosensor L has applications in real sample analysis in environmental and biological samples and building molecular logical devices. To the best of our knowledge, this observation is the first case where a guanidine base bis Schiff base is being utilized for sensing of metal ions.

  DOI：

  10.1016/j.ica.2018.11.021