N-cyclohexyl-2,3-dihydro-1,4-benzodioxine-3-carboxamide

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 苯并二恶烷
• 英文名称: N-cyclohexyl-2,3-dihydro-1,4-benzodioxine-3-carboxamide
• 化学式: C₁₅H₁₉NO₃
• 分子量: 261.32
• InChiKey: ROBCGYAEYRKCRM-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3
• 重原子数：
  19
• 可旋转键数：
  2
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.53
• 拓扑面积：
  47.6
• 氢给体数：
  1
• 氢受体数：
  3

文献信息

• AMINO, AMIDO AND HETEROCYCLIC COMPOUNDS AS MODULATORS OF RAGE ACTIVITY AND USES THEREOF
  申请人：Schmidt Ann Marie

  公开号：US20150094307A1

  公开（公告）日：2015-04-02

  Amino, amido, and heterocyclic compounds are disclosed. The compounds may be prepared as pharmaceutical compositions, and may be used for the prevention and treatment of a variety of conditions in mammals including humans, including by way of non-limiting example, diabetes complications, inflammation, and neurodegeneration, obesity, cancer, ischemia/reperfusion injury, cardiovascular disease and other diseases related to RAGE activity.
• US9364472B2
  申请人：——

  公开号：US9364472B2

  公开（公告）日：2016-06-14
• US9353078B2
  申请人：——

  公开号：US9353078B2

  公开（公告）日：2016-05-31
• [EN] AMINO, AMIDO, AND HETEROCYCLIC COMPOUNDS AS MODULATORS OF RAGE ACTIVITY AND USES THEREOF<br/>[FR] COMPOSÉS AMINO, AMIDO, ET HÉTÉROCYCLIQUES À TITRE DE MODULATEURS DE L'ACTIVITÉ RAGE ET LEURS UTILISATIONS
  申请人：UNIV NEW YORK

  公开号：WO2015050984A1

  公开（公告）日：2015-04-09

  Amino, amido, and heterocyclic compounds are disclosed. The compounds may be prepared as pharmaceutical compositions, and may be used for the prevention and treatment of a variety of conditions in mammals including humans, including by way of non-limiting example, diabetes complications, inflammation, and neurodegeneration, obesity, cancer, ischemia/reperfusion injury, cardiovascular disease and other diseases related to RAGE activity.