Piperazine, 1-benzoyl-4-[1,2-dioxo-2-(1H-pyrrolo[2,3-b]pyridin-3-yl)ethyl]-2-ethyl-

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡咯并吡啶类
• 英文名称: Piperazine, 1-benzoyl-4-[1,2-dioxo-2-(1H-pyrrolo[2,3-b]pyridin-3-yl)ethyl]-2-ethyl-
• 英文别名: 1-(4-benzoyl-3-ethylpiperazin-1-yl)-2-(1H-pyrrolo[2,3-b]pyridin-3-yl)ethane-1,2-dione
• 化学式: C₂₂H₂₂N₄O₃
• 分子量: 390.4
• InChiKey: JSAQJQXBTUQAGL-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.3
• 重原子数：
  29
• 可旋转键数：
  4
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.27
• 拓扑面积：
  86.4
• 氢给体数：
  1
• 氢受体数：
  4

文献信息

• Antiviral azaindole derivatives
  申请人：——

  公开号：US20020119982A1

  公开（公告）日：2002-08-29

  The present invention is directed to a series of chemical entities that express HIV-1 inhibitory activities.

  本发明涉及一系列具有HIV-1抑制活性的化学实体。
• [EN] ANTIVIRAL AZAINDOLE DERIVATIVES<br/>[FR] DERIVES AZA-INDOLES, ANTIVIRAUX
  申请人：BRISTOL MYERS SQUIBB CO

  公开号：WO2001062255A1

  公开（公告）日：2001-08-30

  The present invention is directed to a series of chemical entities that express HIV-1 inhibitory activities.

  本发明涉及一系列具有HIV-1抑制活性的化学实体。
• Composition and films thereof
  申请人：——

  公开号：US20020156193A1

  公开（公告）日：2002-10-24

  The present invention includes a composition comprising (a) at least one propylene polymer coupled by reaction with a coupling amount of poly(sulfonyl azide) sufficient to increase the melt strength of the propylene polymer before coupling at least about 1.5 fold as compared with the resulting coupled propylene polymer; and (b) at least one ethylene polymer wherein the ethylene polymer is present in an amount sufficient to improve film mechanical properties of tear resistance in either the machine direction (MD) and cross direction (CD) as measured by the Elmendorf Tear method (ASTM D-1922) or dart impact strength as measured by the procedure of ASTM D-1709 or a modified method thereof in which the height from which the dart is dropped is decreased from 26″ to 10.5″ (0.66 m to 0.27 m) as compared with a film formed in the same manner using the coupled propylene polymer of (a) alone. Preferably, the propylene polymer is present in an amount of greater than about 50 weight percent of the resulting composition and the ethylene polymer is present in an amount of from about 5 to about 49 weight percent. The invention also includes any blown film blown from a composition of the invention, particularly when blown on a high or low stalk extruder or coextruded as well as the process of blowing such a film. Further, the invention includes any article comprising a composition of the invention or comprising a film of the invention. Particular embodiments are those articles including an institutional liner, consumer liner, heavy duty shipping sack, produce bag, batch inclusion bag, pouch, grocery bag, merchandise bag, packaging, cereal liner, soft paper overwrap, multi-wall bag, lamination or combination thereof, including multi-wall or multilayer configurations thereof. Further, the invention includes the use of a composition of the invention for making a blown film.

  本发明包括一种组合物，该组合物包含：(a) 至少一种丙烯聚合物，该丙烯聚合物通过与聚磺酰叠氮的偶联量反应而偶联，偶联量足以使偶联前丙烯聚合物的熔体强度比偶联后丙烯聚合物的熔体强度至少增加约 1.(b) 至少一种乙烯聚合物，其中乙烯聚合物的含量足以改善薄膜的机械性能，即通过 Elmendorf 撕裂法（ASTM D-1922）测量的机械方向（MD）和横向（CD）的抗撕裂性，或通过 ASTM D-1709 程序或其改进方法测量的飞镖冲击强度，其中飞镖落下的高度从 26″ 降低到 10.5″（0.66 米至 0.27 米）。优选地，丙烯聚合物在所得组合物中的含量大于约 50%，乙烯聚合物的含量为约 5%至约 49%。本发明还包括由本发明组合物吹制的任何吹膜，特别是在高梗或低梗挤出机上吹制或共挤出时，以及吹制这种薄膜的工艺。此外，本发明还包括任何包含本发明组合物或包含本发明薄膜的物品。具体实施例包括机构衬垫、消费者衬垫、重型运输袋、农产品袋、批量包装袋、小袋、杂货袋、商品袋、包装、谷物衬垫、软纸外包装、多层袋、层压或其组合，包括其多层或多层配置。此外，本发明还包括使用本发明的组合物制作吹膜。
• Polyethylene rich/polypropylene blends and their uses
  申请人：——

  公开号：US20030216518A1

  公开（公告）日：2003-11-20

  The present invention includes a blend composition comprising at least one coupled propylene polymer and at least 55 weight percent of at least one ethylene polymer, based on the total weight of the coupled propylene polymer and the ethylene polymer. The invention also includes methods for making the coupled propylene polymer and methods for making the blend composition. The present invention further includes films made from the blend composition.

  本发明包括一种共混组合物，该组合物包含至少一种偶联丙烯聚合物和至少一种乙烯聚合物（基于偶联丙烯聚合物和乙烯聚合物的总重量），其中至少一种偶联丙烯聚合物的重量百分比为 55%。本发明还包括制造偶联丙烯聚合物的方法和制造共混组合物的方法。本发明还包括用该共混组合物制成的薄膜。
• COMPOSITION AND FILMS THEREOF
  申请人：THE DOW CHEMICAL COMPANY

  公开号：EP1198512A1

  公开（公告）日：2002-04-24