N-[(1-methylpyrrolidin-2-yl)methyl]naphthalen-1-amine

• 分子结构分类: 有机化合物 - 苯类化合物 - 萘
• 英文名称: N-[(1-methylpyrrolidin-2-yl)methyl]naphthalen-1-amine
• 化学式: C₁₆H₂₀N₂
• 分子量: 240.34
• InChiKey: XNUJQYGTHGYURE-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.7
• 重原子数：
  18
• 可旋转键数：
  3
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.38
• 拓扑面积：
  15.3
• 氢给体数：
  1
• 氢受体数：
  2

文献信息

• Preparation of 4-substituted-2-buten-4-olides from mucohalic acids
  申请人：Angell Paul

  公开号：US20060004211A1

  公开（公告）日：2006-01-05

  Methods and materials for preparing 4-substituted-2-buten-4-olides are disclosed. The method includes reacting a mucohalic acid with a silyl enol ether or a ketene silyl acetal in the presence of a Lewis acid.

  披露了制备4-取代-2-丁烯-4-内酯的方法和材料。该方法包括将一个粘酸与一个硅基烯醇醚或一个硅基酮缩酮在路易斯酸的存在的条件下进行反应。
• Method for producing eushearlilides
  申请人：TOKYO UNIVERSITY OF SCIENCE FOUNDATION

  公开号：US10696703B2

  公开（公告）日：2020-06-30

  Provided are: eushearilides; a method for producing eushearilides; a production intermediate; and a pharmaceutical composition containing eushearilides. By having the Wittig reaction process, Mukaiyama Aldol reaction process and Macrolactonizaion process serve as key processes, eushearilides represented by formula (I) are efficiently produced.

  本发明提供了：丁香酰胺；一种生产丁香酰胺的方法；一种生产中间体；以及一种含有丁香酰胺的药物组合物。以 Wittig 反应过程、Mukaiyama Aldol 反应过程和 Macrolactonizaion 过程为关键过程，可以高效地生产以式 (I) 为代表的丁晴酰胺。
• METHOD FOR PRODUCING EUSHEARILIDES
  申请人：Tokyo University of Science Foundation

  公开号：EP3214088B1

  公开（公告）日：2020-02-26
• METHOD FOR PRODUCING EUSHEARLILIDES
  申请人：TOKYO UNIVERSITY OF SCIENCE FOUNDATION

  公开号：US20190382425A1

  公开（公告）日：2019-12-19

  Provided are: eushearilides; a method for producing eushearilides; a production intermediate; and a pharmaceutical composition containing eushearilides. By having the Wittig reaction process, Mukaiyama Aldol reaction process and Macrolactonizaion process serve as key processes, eushearilides represented by formula (I) are efficiently produced.

表征谱图