4-Methyl-1-(2-naphthylsulfonyl)piperazine | 5563-92-8

• 分子结构分类: 有机化合物 - 苯类化合物 - 萘
• 英文名称: 4-Methyl-1-(2-naphthylsulfonyl)piperazine
• 英文别名: 1-methyl-4-naphthalen-2-ylsulfonylpiperazine
• CAS: 5563-92-8
• 化学式: C₁₅H₁₈N₂O₂S
• 分子量: 290.4
• InChiKey: VONBSZVCFHEBKP-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.8
• 重原子数：
  20
• 可旋转键数：
  2
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.33
• 拓扑面积：
  49
• 氢给体数：
  0
• 氢受体数：
  4

文献信息

• MEDICAMENT FOR SUPPRESSING MALIGNANT TUMOR METASTASIS
  申请人：NATIONAL CEREBRAL AND CARDIOVASCULAR CENTER

  公开号：US20170014419A1

  公开（公告）日：2017-01-19

  Provided are a novel medicament for suppressing or preventing the metastasis of a malignant tumor such as carcinoma, a novel treatment or prevention method for suppressing or preventing the metastasis of a malignant tumor, etc. The medicament comprises a non-peptidic angiotensin type 2 receptor agonist as an active ingredient. In the medicament, the non-peptidic angiotensin type 2 receptor agonist may be, for example, a sulfonyl malonamide compound. The medicament may be a medicament for use in combination with an anticancer agent and/or an antitumor agent.
• US8461209B2
  申请人：——

  公开号：US8461209B2

  公开（公告）日：2013-06-11