1-(visnagin-9-sulfonamido)-4-nitrobenzene | 106911-49-3

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 苯并吡喃
• 英文名称: 1-(visnagin-9-sulfonamido)-4-nitrobenzene
• 英文别名: 4-methoxy-7-methyl-N-(4-nitrophenyl)-5-oxofuro[3,2-g]chromene-9-sulfonamide
• CAS: 106911-49-3
• 化学式: C₁₉H₁₄N₂O₈S
• 分子量: 430.395
• InChiKey: SGYINWLIMREJAI-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.6
• 重原子数：
  30
• 可旋转键数：
  4
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.11
• 拓扑面积：
  149
• 氢给体数：
  1
• 氢受体数：
  9

反应信息

• 作为产物：
  描述：

  visnagin-9-sulfonyl chloride 、 对苯二胺 在 吡啶 、 氧气 作用下， 以 苯 为溶剂， 反应 3.0h， 以20%的产率得到1-(visnagin-9-sulfonamido)-4-nitrobenzene
  参考文献：
  名称：

  New Types of Mono and Bis Sulfonamides, Tosylamino Acids and Thiosulfonic Ester Derived from Xanthotoxin, Bergapten and Visnagin with Biological Interest

  摘要：

  Xanthotoxin, bergapten, and visnagin sulfonyl chlorides have been reacted with diamines, hydrazine, amino acides, and imidazolidineiminothiones to produce the corresponding mono-, bis-sulfonamide, and tosylamino acid derivatives. Interaction of xanthotoxin-4-sulfonyl chloride with thiohydantoin furnished the respective thiosulfonic ester. The new products exhibited better antibacterial and antifungal activities.

  DOI：

  10.1080/10426500701263521

文献信息

• EL-SHARIEF, A. M. SH.;EL-MAGHRABY, A. A.;ZAHER, M. R.;MOHAMED, Y. A., EGYPT. J. CHEM., 1984, 27, N 4, 443-458
  作者：EL-SHARIEF, A. M. SH.、EL-MAGHRABY, A. A.、ZAHER, M. R.、MOHAMED, Y. A.

  DOI：——

  日期：——
• New Types of Mono and Bis Sulfonamides, Tosylamino Acids and Thiosulfonic Ester Derived from Xanthotoxin, Bergapten and Visnagin with Biological Interest
  作者：A. M. Sh. El-Sharief、S. Y. Al-Raqa

  DOI：10.1080/10426500701263521

  日期：2007.6.1

  Xanthotoxin, bergapten, and visnagin sulfonyl chlorides have been reacted with diamines, hydrazine, amino acides, and imidazolidineiminothiones to produce the corresponding mono-, bis-sulfonamide, and tosylamino acid derivatives. Interaction of xanthotoxin-4-sulfonyl chloride with thiohydantoin furnished the respective thiosulfonic ester. The new products exhibited better antibacterial and antifungal activities.