1-[3,4-Dihydro-2(1H)-isoquinolinyl]-2-[(6-ethoxy-1,3-benzothiazol-2-YL)sulfanyl]-1-ethanone

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 四氢异喹啉
• 英文名称: 1-[3,4-Dihydro-2(1H)-isoquinolinyl]-2-[(6-ethoxy-1,3-benzothiazol-2-YL)sulfanyl]-1-ethanone
• 英文别名: 1-(3,4-dihydro-1H-isoquinolin-2-yl)-2-[(6-ethoxy-1,3-benzothiazol-2-yl)sulfanyl]ethanone
• 化学式: C₂₀H₂₀N₂O₂S₂
• 分子量: 384.5
• InChiKey: DETQYWANHDIIDG-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.6
• 重原子数：
  26
• 可旋转键数：
  5
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.3
• 拓扑面积：
  96
• 氢给体数：
  0
• 氢受体数：
  5

文献信息

• Compounds for modulating TRPV3 function
  申请人：Chong A. Jayhong

  公开号：US20070213321A1

  公开（公告）日：2007-09-13

  The present application relates to compounds and methods for treating pain and other conditions related to TRPV3.

  本申请涉及化合物和治疗疼痛和与TRPV3相关的其他病症的方法。
• Compounds for Modulating TRPV3 Function
  申请人：Chong Jayhong A.

  公开号：US20100273777A1

  公开（公告）日：2010-10-28

  The present application relates to compounds and methods for treating pain and other conditions related to TRPV3.

  本申请涉及化合物和治疗疼痛和与TRPV3相关的其他疾病的方法。
• COMPOUNDS FOR MODULATING TRPV3 FUNCTION
  申请人：Chong Jayhong A.

  公开号：US20150299225A1

  公开（公告）日：2015-10-22

  The present application relates to compounds and methods for treating pain and other conditions related to TRPV3.

  本申请涉及化合物和治疗与TRPV3相关的疼痛和其他疾病的方法。
• SMALL MOLECULE INHIBITORS FOR THE TREATMENT OR PREVENTION OF DENGUE VIRUS INFECTION
  申请人：Siga Technologies, Inc.

  公开号：EP2293671A1

  公开（公告）日：2011-03-16
• SAMLL MOLECULE INHIBITORS FOR THE TREATMENT OR PREVENTION OF DENGUE VIRUS INFECTION
  申请人：Byrd Chelsea M.

  公开号：US20110158940A1

  公开（公告）日：2011-06-30

  Methods and pharmaceutical compositions for treating viral infections, by administering certain compounds in therapeutically effective amounts are disclosed. Methods of using the compounds and pharmaceutical compositions thereof are also disclosed. In particular, the treatment and prophylaxis of viral infections such as caused by flavivirus is disclosed, i.e., including but not limited to, Dengue virus, West Nile virus, yellow fever virus, Japanese encephalitis virus, and tick-borne encephalitis virus.