N-β-Naphthyl-fumaramsaeure | 31183-15-0

• 分子结构分类: 有机化合物 - 苯类化合物 - 萘
• 英文名称: N-β-Naphthyl-fumaramsaeure
• 英文别名: 4-(Naphthalen-2-ylamino)-4-oxobut-2-enoic acid；(E)-4-(naphthalen-2-ylamino)-4-oxobut-2-enoic acid
• CAS: 31183-15-0
• 化学式: C₁₄H₁₁NO₃
• 分子量: 241.246
• InChiKey: MJBXLSQXZHYTSR-BQYQJAHWSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.1
• 重原子数：
  18
• 可旋转键数：
  3
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  66.4
• 氢给体数：
  2
• 氢受体数：
  3

文献信息

• HEME OXYGENASE INHIBITORS, SCREENING METHODS FOR HEME OXYGENASE INHIBITORS AND METHODS OF USE OF HEME OXYGENASE INHIBITORS FOR ANTIMICROBIAL THERAPY
  申请人：Wilks Angela

  公开号：US20100081661A1

  公开（公告）日：2010-04-01

  Inhibitors of microbial heme oxygenase and their use for treatment of microbial infections and bioremediation. The inhibitors of microbial heme oxygenase are useful against a new class of antimicrobial agents to target infections that are persistently difficult to combat with the current spectrum of antimicrobial agents. Screening methods for selecting inhibitors of microbial heme oxygenase.