2-(2-Methyldec-1-en-5-yn-4-yl)naphthalene | 1009556-54-0

• 分子结构分类: 有机化合物 - 苯类化合物 - 萘
• 英文名称: 2-(2-Methyldec-1-en-5-yn-4-yl)naphthalene
• 英文别名: 2-(2-methyldec-1-en-5-yn-4-yl)naphthalene
• CAS: 1009556-54-0
• 化学式: C₂₁H₂₄
• 分子量: 276.422
• InChiKey: VTTWHRHLTRGSOL-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  7.3
• 重原子数：
  21
• 可旋转键数：
  5
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.33
• 拓扑面积：
  0
• 氢给体数：
  0
• 氢受体数：
  0

反应信息

• 作为产物：
  描述：

  1-(naphthalen-2-yl)hept-2-yn-1-ol 、 异丁烯基三甲基硅烷 在 scandium tris(trifluoromethanesulfonate) 作用下， 以 乙腈 为溶剂， 反应 0.5h， 以86%的产率得到2-(2-Methyldec-1-en-5-yn-4-yl)naphthalene
  参考文献：
  名称：

  Copper(II)-catalyzed allylation of propargylic and allylic alcohols by allylsilanes: a facile synthesis of 1,5-enynes

  摘要：

  Propargylic alcohols undergo smooth deoxygenative allylation with allylsilanes in the presence of a solution of 10 mol % of copper(II) tetrafluoroborate in acetonitrile to afford the corresponding 1,5-enynes in good to high yields under mild and neutral conditions. Scandium triflate is also found to catalyze efficiently the nucleophilic substitution of propargylic alcohols with allylsilanes. (c) 2007 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2007.11.143

文献信息

• Copper(II)-catalyzed allylation of propargylic and allylic alcohols by allylsilanes: a facile synthesis of 1,5-enynes
  作者：J.S. Yadav、B.V. Subba Reddy、T. Srinivasa Rao、K.V. Raghavendra Rao

  DOI：10.1016/j.tetlet.2007.11.143

  日期：2008.1

  Propargylic alcohols undergo smooth deoxygenative allylation with allylsilanes in the presence of a solution of 10 mol % of copper(II) tetrafluoroborate in acetonitrile to afford the corresponding 1,5-enynes in good to high yields under mild and neutral conditions. Scandium triflate is also found to catalyze efficiently the nucleophilic substitution of propargylic alcohols with allylsilanes. (c) 2007 Elsevier Ltd. All rights reserved.