(3E)-3-(5-phenyl-3H-1,2dithiol-3-ylidene)-2H-chromene-2,4(3H)-dione | 63520-86-5

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 苯并吡喃
• 英文名称: (3E)-3-(5-phenyl-3H-1,2dithiol-3-ylidene)-2H-chromene-2,4(3H)-dione
• 英文别名: (3E)-3-(5-phenyldithiol-3-ylidene)chromene-2,4-dione
• CAS: 63520-86-5
• 化学式: C₁₈H₁₀O₃S₂
• 分子量: 338.408
• InChiKey: QEGUSOMWJVEWSI-FOCLMDBBSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4
• 重原子数：
  23
• 可旋转键数：
  1
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  94
• 氢给体数：
  0
• 氢受体数：
  5

文献信息

• EGR1 TARGETING MOLECULES FOR THE TREATMENT OF INFLAMMATORY AND HYPERPROLIFERATIVE CONDITIONS
  申请人：The Medical Research, Infrastructure and Health Services Fund of the Tel Aviv Medical Center

  公开号：US20180289728A1

  公开（公告）日：2018-10-11

  A method of treating an inflammation or a hyperproliferative disease in a subject in need thereof is disclosed. The method comprising administering to the subject a therapeutically effective amount of a compound selected from the group consisting of: a compound represented by Formula I: or a pharmaceutically acceptable salt thereof, a compound represented by Formula II: and a compound represented by Formula III: wherein the variables in Formulae I, II and III are as defined in the specification.