3-[4-(Azidomethyl)phenyl]propanoic acid

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 苯丙酸
• 英文名称: 3-[4-(Azidomethyl)phenyl]propanoic acid
• 英文别名: 3-[4-(azidomethyl)phenyl]propanoic acid
• 化学式: C10H11N3O2
• 分子量: 205.21
• InChiKey: BVILUXHDPSUZLS-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.6
• 重原子数：
  15
• 可旋转键数：
  5
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.3
• 拓扑面积：
  51.7
• 氢给体数：
  1
• 氢受体数：
  4

文献信息

• [EN] MODIFIED AMINO ACIDS COMPRISING TETRAZINE FUNCTIONAL GROUPS, METHODS OF PREPARATION, AND METHODS OF THEIR USE<br/>[FR] ACIDES AMINÉS MODIFIÉS COMPRENANT DES GROUPES FONCTIONNELS DE TÉTRAZINE, PROCÉDÉS DE PRÉPARATION ET PROCÉDÉS D'UTILISATION ASSOCIÉS
  申请人：SUTRO BIOPHARMA INC

  公开号：WO2015054658A1

  公开（公告）日：2015-04-16

  Provided herein are modified amino acids comprising a tetrazine groups according to Formula I: polypeptides, antibodies, payloads and conjugates comprising these modified amino acid residues derived from the modified amino acids, and methods of producing the polypeptides, antibodies, payloads and conjugates comprising the modified amino acid residues. The polypeptides, antibodies, payloads and conjugates are useful in methods of treatment and prevention, methods of detection and methods of diagnosis.

  本文提供了一种包含四唑基团的修饰氨基酸，其符合公式I：由这些修饰氨基酸衍生的多肽、抗体、荷载物和结合物，以及制备包含修饰氨基酸残基的多肽、抗体、荷载物和结合物的方法。这些多肽、抗体、荷载物和结合物在治疗和预防方法、检测方法和诊断方法中非常有用。
• [EN] MODIFIED AMINO ACIDS COMPRISING AN AZIDO GROUP<br/>[FR] ACIDES AMINÉS MODIFIÉS COMPRENANT UN GROUPE AZIDO
  申请人：SUTRO BIOPHARMA INC

  公开号：WO2014036492A1

  公开（公告）日：2014-03-06

  Provided herein are modified amino acids comprising an azido group, polypeptides, antibodies and conjugates comprising the modified amino acids, and methods of producing the polypeptides, antibodies and conjugates comprising the modified amino acids. The polypeptides, antibodies and conjugates are useful in methods of treatment and prevention, methods of detection and methods of diagnosis.