[(2R,5S)-2-(5-methyl-1,2,4-oxadiazol-3-yl)-7-oxo-1,6-diazabicyclo[3.2.1]octan-6-yl] hydrogen sulfate

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 二氮杂卓
• 英文名称: [(2R,5S)-2-(5-methyl-1,2,4-oxadiazol-3-yl)-7-oxo-1,6-diazabicyclo[3.2.1]octan-6-yl] hydrogen sulfate
• 化学式: C₉H₁₂N₄O₆S
• 分子量: 304.28
• InChiKey: YVQGORFRIRIPSK-NKWVEPMBSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -0.6
• 重原子数：
  20
• 可旋转键数：
  3
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.67
• 拓扑面积：
  134
• 氢给体数：
  1
• 氢受体数：
  8

文献信息

• 1,6-Diazabicyclo [3,2,1] octan-7-one derivatives and their use in the treatment of bacterial infections
  申请人：Bhagwat Sachin

  公开号：US20140088068A1

  公开（公告）日：2014-03-27

  Compounds of Formula (I), their preparation and use in preventing or treating bacterial infections are disclosed.

  公式（I）化合物的制备和在预防或治疗细菌感染中的用途被披露。
• ANTIVIRAL PHOSPHONATE ANALOGS
  申请人：Boojamra Constantine G.

  公开号：US20090275535A1

  公开（公告）日：2009-11-05

  The invention is related to phosphorus substituted compounds with antiviral activity, compositions containing such compounds, and therapeutic methods that include the administration of such compounds, as well as to processes and intermediates useful for preparing such compounds.

  这项发明涉及具有抗病毒活性的磷取代化合物，包含这种化合物的组合物以及包括给予这种化合物的治疗方法，还包括用于制备这种化合物的过程和中间体。
• Nitrogen containing heterocyclic compounds
  申请人：BHAGWAT Sachin

  公开号：US20140288064A1

  公开（公告）日：2014-09-25

  Compounds of Formula (I), their preparation and use in preventing or treating bacterial infections are disclosed.

  本发明公开了化学式（I）的化合物，其制备以及在预防或治疗细菌感染方面的用途。
• NITROGEN CONTAINING HETEROCYCLIC COMPOUNDS
  申请人：WOCKHARDT LIMITED

  公开号：US20150336957A1

  公开（公告）日：2015-11-26

  Compounds of Formula (I), their preparation and use in preventing or treating bacterial infections are disclosed.

  本发明揭示了式(I)的化合物，其制备方法以及在预防或治疗细菌感染方面的用途。
• 1,6-DIAZABICYCLO[3,2,1]OCTAN-7-ONE DERIVATIVES AND THEIR USE IN THE TREATMENT OF BACTERIAL INFECTIONS
  申请人：Wockhardt Limited

  公开号：EP2872510B1

  公开（公告）日：2016-11-23