[Methyl-[4-(2-tricyclo[9.4.0.03,8]pentadeca-1(15),3,5,7,9,11,13-heptaenylidene)butyl]amino]methyl 5-(dithiolan-3-yl)pentanoate

• 分子结构分类: 有机化合物 - 苯类化合物 - 二苯并环庚烯
• 英文名称: [Methyl-[4-(2-tricyclo[9.4.0.03,8]pentadeca-1(15),3,5,7,9,11,13-heptaenylidene)butyl]amino]methyl 5-(dithiolan-3-yl)pentanoate
• 英文别名: [methyl-[4-(2-tricyclo[9.4.0.03,8]pentadeca-1(15),3,5,7,9,11,13-heptaenylidene)butyl]amino]methyl 5-(dithiolan-3-yl)pentanoate
• 化学式: C₂₉H₃₅NO₂S₂
• 分子量: 493.7
• InChiKey: RULSQSIPDRIBLV-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  6.8
• 重原子数：
  34
• 可旋转键数：
  12
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.41
• 拓扑面积：
  80.1
• 氢给体数：
  0
• 氢受体数：
  5

文献信息

• [EN] COMPOSITIONS AND METHODS FOR THE TREATMENT OF FIBROMYALGIA PAIN<br/>[FR] COMPOSITIONS ET MÉTHODES DE TRAITEMENT DE LA DOULEUR FIBROMYALGIQUE
  申请人：KANDULA MAHESH

  公开号：WO2013168004A2

  公开（公告）日：2013-11-14

  The invention relates to the compounds of formula (I) or its pharmaceutical acceptable salts, as well as polymorphs, solvates, enantiomers, stereoisomers and hydrates thereof. The pharmaceutical compositions comprising an effective amount of compounds of formula (I), and methods for the treatment of fibromyalgia pain may be formulated for oral, buccal, rectal, topical, transdermal, transmucosal, intravenous, parenteral administration, syrup, or injection. Such compositions may be used to treatment of injury, post-operative pain, osteoarthritis, rheumatoid arthritis, multiple sclerosis, spinal cord injury, migraine, HIV related neuropathic pain, post herpetic neuralgia, diabetic neuropathy, bipolar depression, stress, cancer pain, and lower back pain.