4-[2-Butoxy-2-(4-hydroxy-3-methoxyphenyl)ethyl]-2-methoxyphenol

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 二苯乙烯类
• 英文名称: 4-[2-Butoxy-2-(4-hydroxy-3-methoxyphenyl)ethyl]-2-methoxyphenol
• 英文别名: 4-[2-butoxy-2-(4-hydroxy-3-methoxyphenyl)ethyl]-2-methoxyphenol
• 化学式: C₂₀H₂₆O₅
• 分子量: 346.4
• InChiKey: YAMAXITYKGHYBF-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4
• 重原子数：
  25
• 可旋转键数：
  9
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.4
• 拓扑面积：
  68.2
• 氢给体数：
  2
• 氢受体数：
  5

文献信息

• Topical NSAID Compositions Having Sensate Component
  申请人：ZHANG Joanna

  公开号：US20140113971A1

  公开（公告）日：2014-04-24

  Topical pharmaceutical compositions comprising a topically administrable NSAID, a sensate agent and optionally a self-warming system, when administered to a patient in need thereof, provide significant improvements in the rate and extent of skin absorption, as well as impart a sensation of rapid and complete relief from pain.