5-[[Hydroxy-[hydroxy-[hydroxy(methyl)phosphoryl]oxyphosphoryl]oxyphosphoryl]amino]naphthalene-1-sulfonic acid

• 分子结构分类: 有机化合物 - 苯类化合物 - 萘
• 英文名称: 5-[[Hydroxy-[hydroxy-[hydroxy(methyl)phosphoryl]oxyphosphoryl]oxyphosphoryl]amino]naphthalene-1-sulfonic acid
• 英文别名: 5-[[hydroxy-[hydroxy-[hydroxy(methyl)phosphoryl]oxyphosphoryl]oxyphosphoryl]amino]naphthalene-1-sulfonic acid
• 化学式: C₁₁H₁₄NO₁₁P₃S
• 分子量: 461.22
• InChiKey: LXNVOPYBJAIMOV-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -0.9
• 重原子数：
  27
• 可旋转键数：
  7
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.09
• 拓扑面积：
  205
• 氢给体数：
  5
• 氢受体数：
  12

文献信息

• ENZYMATIC NUCLEIC ACID SYNTHESIS: COMPOSITIONS AND METHODS FOR INHIBITING PYROPHOSPHOROLYSIS
  申请人：LIFE TECHNOLOGIES CORPORATION

  公开号：US20140127781A1

  公开（公告）日：2014-05-08

  Nucleotide triphosphate probes containing a molecular and/or atomic tag on a γ and/or β phosphate group and/or a base moiety having a detectable property are disclosed, and kits and method for using the tagged nucleotides in sequencing reactions and various assay. Also, phosphate and polyphosphate molecular fidelity altering agents are disclosed.