2-(4-Aza-1-azoniabicyclo[2.2.2]octan-1-yl)-1-naphthalen-1-ylethanone;bromide

• 分子结构分类: 有机化合物 - 苯类化合物 - 萘
• 英文名称: 2-(4-Aza-1-azoniabicyclo[2.2.2]octan-1-yl)-1-naphthalen-1-ylethanone;bromide
• 英文别名: 2-(4-aza-1-azoniabicyclo[2.2.2]octan-1-yl)-1-naphthalen-1-ylethanone;bromide
• 化学式: C18H21BrN2O
• 分子量: 361.3
• InChiKey: CUIXKQOOWVBFRQ-UHFFFAOYSA-M

计算性质

• 辛醇/水分配系数(LogP)：
  -0.83
• 重原子数：
  22
• 可旋转键数：
  3
• 环数：
  5.0
• sp3杂化的碳原子比例：
  0.39
• 拓扑面积：
  20.3
• 氢给体数：
  0
• 氢受体数：
  3

文献信息

• Substrates, systems, and methods for array synthesis and biomolecular analysis
  申请人：Vibrant Holdings, LLC

  公开号：US10286376B2

  公开（公告）日：2019-05-14

  Disclosed herein are formulations, substrates, and arrays. In certain embodiments, substrates and arrays comprise a porous layer for synthesis and attachment of polymers or biomolecules. Also disclosed herein are methods for manufacturing and using the formulations, substrates, and arrays, including porous arrays. Also disclosed herein are formulations and methods for one-step coupling, e.g., for synthesis of peptides in an N->C orientation. In some embodiments, disclosed herein are formulations and methods for high efficiency coupling of biomolecules to a substrate.

  本文公开了配方、基底和阵列。在某些实施方案中，基底和阵列包括用于合成和附着聚合物或生物分子的多孔层。本文还公开了制造和使用配方、基底和阵列（包括多孔阵列）的方法。本文还公开了用于一步偶联的配方和方法，例如用于合成 N->C 取向的肽。在某些实施方案中，本文公开了生物大分子与基质高效偶联的配方和方法。
• SUBSTRATES, SYSTEMS, AND METHODS FOR ARRAY SYNTHESIS AND BIOMOLECULAR ANALYSIS
  申请人：Vibrant Holdings, LLC

  公开号：EP2920272A2

  公开（公告）日：2015-09-23
• METHODS FOR ARRAY SYNTHESIS
  申请人：Vibrant Holdings, LLC

  公开号：EP2920272B1

  公开（公告）日：2019-08-21
• Substrates, Systems, and Methods for Array Synthesis and Biomolecular Analysis
  申请人：Vibrant Holdings, LLC

  公开号：US20160288080A1

  公开（公告）日：2016-10-06

  Disclosed herein are formulations, substrates, and arrays. In certain embodiments, substrates and arrays comprise a porous layer for synthesis and attachment of polymers or biomolecules. Also disclosed herein are methods for manufacturing and using the formulations, substrates, and arrays, including porous arrays. Also disclosed herein are formulations and methods for one-step coupling, e.g., for synthesis of peptides in an N->C orientation. In some embodiments, disclosed herein are formulations and methods for high efficiency coupling of biomolecules to a substrate.
• [EN] SUBSTRATES, SYSTEMS, AND METHODS FOR ARRAY SYNTHESIS AND BIOMOLECULAR ANALYSIS<br/>[FR] SUBSTRATS, SYSTÈMES ET PROCÉDÉS POUR LA SYNTHÈSE DE RÉSEAU ET L'ANALYSE BIOMOLÉCULAIRE
  申请人：VIBRANT HOLDINGS LLC

  公开号：WO2014078606A2

  公开（公告）日：2014-05-22

  Disclosed herein are formulations, substrates, and arrays. In certain embodiments, substrates and arrays comprise a porous layer for synthesis and attachment of polymers or biomolecules. Also disclosed herein are methods for manufacturing and using the formulations, substrates, and arrays, including porous arrays. Also disclosed herein are formulations and methods for one-step coupling, e.g., for synthesis of peptides in an N->C orientation. In some embodiments, disclosed herein are formulations and methods for high efficiency coupling of biomolecules to a substrate.