3,4-diaza-2,2-dimethyl-1-oxa-6,10-dithiaspiro[4.5]dec-3-ene | 328249-78-1

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 二噻烷
• 英文名称: 3,4-diaza-2,2-dimethyl-1-oxa-6,10-dithiaspiro[4.5]dec-3-ene
• 英文别名: 2,2-Dimethyl-1-oxa-6,10-dithia-3,4-diazaspiro[4.5]dec-3-ene
• CAS: 328249-78-1
• 化学式: C₇H₁₂N₂OS₂
• 分子量: 204.317
• InChiKey: SYJUMUQDHNQMPT-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.1
• 重原子数：
  12
• 可旋转键数：
  0
• 环数：
  2.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  84.6
• 氢给体数：
  0
• 氢受体数：
  5

反应信息

• 作为反应物：
  描述：

  1-isocyanatocyclohex-1-ene 、 3,4-diaza-2,2-dimethyl-1-oxa-6,10-dithiaspiro[4.5]dec-3-ene 以 苯 为溶剂， 反应 1.25h， 以59 mg的产率得到7-(1,3-dithian-2-yl)spiro[1,3-dithian-2,3'-3,4',5',6',3a'-pentahydroindole]-8-one
  参考文献：
  名称：

  Bis(alkylthio)carbenes as Novel Reagents for Organic Synthesis

  摘要：

  Bis(alkylthio)carbenes have been shown to be a useful class of reactive intermediates for applications to organic synthesis. Substituted hydroindolanes, isatins and hydroquinolones can be prepared by the addition of these carbenes to vinyl isocyanates. (C) 2000 Elsevier Science Ltd. All rights reserved.

  DOI：

  10.1016/s0040-4020(00)00855-3
• 作为产物：
  描述：

  N-(1-aza-2-methylprop-1-enyl)(2'-sulfanylpropylthio)carboxamide 在 对甲苯磺酸 作用下， 以 二氯甲烷 为溶剂， 反应 3.5h， 生成 3,4-diaza-2,2-dimethyl-1-oxa-6,10-dithiaspiro[4.5]dec-3-ene
  参考文献：
  名称：

  Bis(alkylthio)carbenes as Novel Reagents for Organic Synthesis

  摘要：

  Bis(alkylthio)carbenes have been shown to be a useful class of reactive intermediates for applications to organic synthesis. Substituted hydroindolanes, isatins and hydroquinolones can be prepared by the addition of these carbenes to vinyl isocyanates. (C) 2000 Elsevier Science Ltd. All rights reserved.

  DOI：

  10.1016/s0040-4020(00)00855-3

文献信息

• Bis(alkylthio)carbenes as Novel Reagents for Organic Synthesis
  作者：James H. Rigby、Stephane Laurent、Weitong Dong、M.Diana Danca

  DOI：10.1016/s0040-4020(00)00855-3

  日期：2000.12

  Bis(alkylthio)carbenes have been shown to be a useful class of reactive intermediates for applications to organic synthesis. Substituted hydroindolanes, isatins and hydroquinolones can be prepared by the addition of these carbenes to vinyl isocyanates. (C) 2000 Elsevier Science Ltd. All rights reserved.