8-Sulfanylnaphthalene-1-carbodithioic acid

• 分子结构分类: 有机化合物 - 苯类化合物 - 萘
• 英文名称: 8-Sulfanylnaphthalene-1-carbodithioic acid
• 英文别名: 8-sulfanylnaphthalene-1-carbodithioic acid
• 化学式: C₁₁H₈S₃
• 分子量: 236.4
• InChiKey: KMMRWZBULZUKNJ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4
• 重原子数：
  14
• 可旋转键数：
  1
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  34.1
• 氢给体数：
  2
• 氢受体数：
  3

文献信息

• NOVEL SYNTHETIC ANTIOXIDANTS AND THEIR USES
  申请人：Lu Yansong

  公开号：US20150336884A1

  公开（公告）日：2015-11-26

  The present invention relates to synthetic organic antioxidants of small molecules. The novel dithiol-containing compounds in this invention possess strongest possible capability as both scavenger for free radicals and antioxidant. This invention is directed to novel molecules as prodrugs of the novel dithiol-containing compounds, their rational design, their feasible preparation route by means of synthetic organic chemistry, and their potential uses in application to treatment and/or prevention of major diseases associated with oxidative stress, such as Alzheimer's disease, Parkinson's disease, cancer, diabetes, HIV, acne, cardiovascular disease, renal disease, hypertension, hypercholesterolemia, hyperlipidemia, rheumatoid arthritis, inflammation, pain, aging, stroke, cataract, glaucoma, age-related macular degeneration, etc.
• US9994519B2
  申请人：——

  公开号：US9994519B2

  公开（公告）日：2018-06-12
• [EN] NOVEL SYNTHETIC ANTIOXIDANTS AND THEIR USES<br/>[FR] NOUVEAUX ANTIOXYDANTS DE SYNTHÈSE ET LEURS UTILISATIONS
  申请人：LU YANSONG

  公开号：WO2014084898A1

  公开（公告）日：2014-06-05

  The present invention relates to synthetic organic antioxidants of small molecules. The novel dithiol-containing compounds in this invention possess strongest possible capability as both scavenger for free radicals and antioxidant. This invention is directed to novel molecules as prodrugs of the novel dithiol-containing compounds, their rational design, their feasible preparation route by means of synthetic organic chemistry, and their potential uses in application to treatment and/or prevention of major diseases associated with oxidative stress, such as Alzheimer's disease, Parkinson's disease, cancer, diabetes, HIV, acne, cardiovascular disease, renal disease, hypertension, hypercholesterolemia, hyperlipidemia, rheumatoid arthritis, inflammation, pain, aging, stroke, cataract, glaucoma, age-related macular degeneration, etc.