2-(1,4-dioxan-2-yl)-N,N-dimethylethanamine

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 二恶烷
• 英文名称: 2-(1,4-dioxan-2-yl)-N,N-dimethylethanamine
• 化学式: C₈H₁₇NO₂
• 分子量: 159.23
• InChiKey: YEFNILYCCXNWKZ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.2
• 重原子数：
  11
• 可旋转键数：
  3
• 环数：
  1.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  21.7
• 氢给体数：
  0
• 氢受体数：
  3

文献信息

• NOVEL PHARMACEUTICAL FORMULATION AND ITS USE IN THE TREATMENT OF PERIODONTAL DISEASE
  申请人：PerioC Ltd

  公开号：EP3498290A1

  公开（公告）日：2019-06-19

  The present invention relates to novel treatments of periodontal disease by administering a suitable formulation of a cyclophilin inhibitor. The present invention further relates to novel pharmaceutical compositions containing said cyclophilin inhibitor compounds.

  本发明涉及通过施用环嗜蛋白抑制剂的适当制剂来治疗牙周病的新型方法。本发明还涉及含有所述环嗜蛋白抑制剂化合物的新型药物组合物。
• Pharmaceutical formulations and their use in the treatment of periodontal disease
  申请人：PERIOC LTD

  公开号：US10471058B2

  公开（公告）日：2019-11-12

  The present invention relates to novel treatments of periodontal disease by administering a suitable formulation of a cyclophilin inhibitor. The present invention further relates to novel pharmaceutical compositions containing said cyclophilin inhibitor compounds.

  本发明涉及通过施用环嗜蛋白抑制剂的适当制剂来治疗牙周病的新型方法。 本发明还涉及含有所述环嗜蛋白抑制剂化合物的新型药物组合物。
• NOVEL PHARMACEUTICAL FORMULATIONS AND THEIR USE IN THE TREATMENT OF PERIODONTAL DISEASE
  申请人：PerioC Ltd

  公开号：EP2931299B1

  公开（公告）日：2019-02-06
• [EN] NOVEL PHARMACEUTICAL FORMULATIONS AND THEIR USE IN THE TREATMENT OF PERIODONTAL DISEASE<br/>[FR] NOUVELLES FORMULATIONS PHARMACEUTIQUES ET LEUR UTILISATION DANS LE TRAITEMENT D'UNE MALADIE PARODONTALE
  申请人：PERIOC LTD

  公开号：WO2014091239A1

  公开（公告）日：2014-06-19

  The present invention relates to novel treatments of periodontal disease by administering a suitable formulation of a cyclophilin inhibitor. The present invention further relates to novel pharmaceutical compositions containing said cyclophilin inhibitor compounds.