1-[5-[4-(2-Bromoethyl)phenoxy]-1-(3,4-dimethylphenyl)pentan-2-yl]-3,5-difluorobenzene

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 二苯乙烯类
• 英文名称: 1-[5-[4-(2-Bromoethyl)phenoxy]-1-(3,4-dimethylphenyl)pentan-2-yl]-3,5-difluorobenzene
• 英文别名: 1-[5-[4-(2-bromoethyl)phenoxy]-1-(3,4-dimethylphenyl)pentan-2-yl]-3,5-difluorobenzene
• 化学式: C₂₇H₂₉BrF₂O
• 分子量: 487.4
• InChiKey: FZJDUNJHKYMTAW-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  8.3
• 重原子数：
  31
• 可旋转键数：
  10
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.33
• 拓扑面积：
  9.2
• 氢给体数：
  0
• 氢受体数：
  3

文献信息

• AMINO DIOL DERIVATIVES AS SPHINGOSINE 1-PHOSPHATE (S1P) RECEPTOR MODULATORS
  申请人：ALLERGAN, INC.

  公开号：US20140221498A1

  公开（公告）日：2014-08-07

  The present invention relates to amino diol derivatives, processes for preparing them, pharmaceutical compositions containing them and their use as pharmaceuticals as modulators of sphingosine-1-phosphate receptors.
• [EN] AMINO DIOL DERIVATIVES AS SPHINGOSINE 1-PHOSPHATE (S1P) RECEPTOR MODULATORS<br/>[FR] DÉRIVÉS D'AMINO-DIOLS UTILISÉS EN TANT QUE MODULATEURS DES RÉCEPTEURS DE LA SPHINGOSINE 1-PHOSPHATE (S1P)
  申请人：ALLERGAN INC

  公开号：WO2014124013A1

  公开（公告）日：2014-08-14

  The present invention relates to amino diol derivatives, processes for preparing them, pharmaceutical compositions containing them and their use as pharmaceuticals as modulators of sphingosine-1-phosphate receptors.