8-Hydroxy-4-methylidenenaphthalen-1-one

• 分子结构分类: 有机化合物 - 苯类化合物 - 萘
• 英文名称: 8-Hydroxy-4-methylidenenaphthalen-1-one
• 英文别名: 8-hydroxy-4-methylidenenaphthalen-1-one
• 化学式: C₁₁H₈O₂
• 分子量: 172.18
• InChiKey: NVFXPPADHONPIZ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.5
• 重原子数：
  13
• 可旋转键数：
  0
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  37.3
• 氢给体数：
  1
• 氢受体数：
  2

文献信息

• Small Molecule CD38 Inhibitors and Methods of Using Same
  申请人：Sinclair David A.

  公开号：US20140221319A1

  公开（公告）日：2014-08-07

  The invention provides methods and compositions for inhibiting CD 38 activity, and methods of treating or preventing various disorders associated with CD38 activity.
• SMALL MOLECULE CD38 INHIBITORS AND METHODS OF USING SAME
  申请人：President and Fellows of Harvard College

  公开号：US20180085383A1

  公开（公告）日：2018-03-29

  The invention provides methods and compositions for inhibiting CD38 activity, and methods of treating or preventing various disorders associated with CD38 activity.