[6-[6-[[(2R,3S,5R)-5-(2-amino-6-oxo-1H-purin-9-yl)-3-methoxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxyhexylcarbamoyl]-6'-(2,2-dimethylpropanoyloxy)-3-oxospiro[2-benzofuran-1,9'-xanthene]-3'-yl] 2,2-dimethylpropanoate

• 分子结构分类: 有机化合物 - 核苷、核苷酸和类似物 - 嘌呤核苷酸
• 英文名称: [6-[6-[[(2R,3S,5R)-5-(2-amino-6-oxo-1H-purin-9-yl)-3-methoxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxyhexylcarbamoyl]-6'-(2,2-dimethylpropanoyloxy)-3-oxospiro[2-benzofuran-1,9'-xanthene]-3'-yl] 2,2-dimethylpropanoate
• 化学式: C₄₈H₅₅N₆O₁₅P
• 分子量: 987.0
• InChiKey: XPYBNSGREOEGNN-HKIDPNTFSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.6
• 重原子数：
  70
• 可旋转键数：
  20
• 环数：
  8.0
• sp3杂化的碳原子比例：
  0.44
• 拓扑面积：
  277
• 氢给体数：
  4
• 氢受体数：
  16

文献信息

• REMOTE ASSEMBLY OF TARGETED NANOPARTICLES USING COMPLEMENTARY OLIGONUCLEOTIDE LINKERS
  申请人：Mallinckrodt LLC

  公开号：US20140234217A1

  公开（公告）日：2014-08-21

  The present invention provides targeted delivery compositions and their methods of use in treating and diagnosing a disease state in a subject. Components of the targeted delivery compositions are put together through duplex formation between oligonucleotides.