7-Methyl-2,3-dihydro-1,4-benzodioxine-5,6-diol

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 苯并二恶烷
• 英文名称: 7-Methyl-2,3-dihydro-1,4-benzodioxine-5,6-diol
• 英文别名: 7-methyl-2,3-dihydro-1,4-benzodioxine-5,6-diol
• 化学式: C₉H₁₀O₄
• 分子量: 182.17
• InChiKey: MKNZEWAXUQARRU-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.3
• 重原子数：
  13
• 可旋转键数：
  0
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.33
• 拓扑面积：
  58.9
• 氢给体数：
  2
• 氢受体数：
  4

文献信息

• GAMMA-DIKETONES FOR TREATMENT AND PREVENTION OF AGING SKIN AND WRINKLES
  申请人：Samumed, LLC

  公开号：US20160206540A1

  公开（公告）日：2016-07-21

  The present disclosure relates to compounds, cosmetic or dermopharmaceutical compositions comprising the same, and methods for using the compounds or compositions for treating, protecting, and/or improving the condition and/or aesthetic appearance of skin, for example, treating, preventing, ameliorating, reducing and/or eliminating fine lines and/or wrinkles of skin, or improving the appearance of fine lines and/or or wrinkles of skin comprising application of the compounds or compositions disclosed.
• US9795550B2
  申请人：——

  公开号：US9795550B2

  公开（公告）日：2017-10-24
• [EN] GAMMA-DIKETONES AS WNT/BETA -CATENIN SIGNALING PATHWAY ACTIVATORS<br/>[FR] GAMMA-DICÉTONES EN TANT QU'ACTIVATEURS DE LA VOIE DE SIGNALISATION WNT/&Bgr;-CATÉNINE
  申请人：SAMUMED LLC

  公开号：WO2014130869A1

  公开（公告）日：2014-08-28

  The present disclosure provides ƴ-diketones or analogs thereof, that activate Wnt/β-catenin signaling and thus treat or prevent diseases related to signal transduction, such as osteoporosis and osteoarthropathy; osteogenesis imperfecta, bone defects, bone fractures, periodontal disease, otosclerosis, wound healing, craniofacial defects, oncolytic bone disease, traumatic brain injuries or spine injuries, brain atrophy/neurological disorders related to the differentiation and development of the central nervous system, including Parkinson's disease, strokes, ischemic cerebral disease, epilepsy, Alzheimer's disease, depression, bipolar disorder, schizophrenia; otic disorders like cochlear hair cell loss; eye diseases such as age related macular degeneration, diabetic macular edema or retinitis pigmentosa and diseases related to differentiation and growth of stem cell, such as hair loss, hematopoiesis related diseases and tissue regeneration related diseases.