N-[(6aR,10aR)-3-(1,1-difluoropentyl)-6,6,9-trimethyl-6a,7,8,10a-tetrahydrobenzo[c]chromen-1-yl]-N-(2-nitrooxyethyl)carbamate

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 苯并吡喃
• 英文名称: N-[(6aR,10aR)-3-(1,1-difluoropentyl)-6,6,9-trimethyl-6a,7,8,10a-tetrahydrobenzo[c]chromen-1-yl]-N-(2-nitrooxyethyl)carbamate
• 化学式: C24H31F2N2O6-
• 分子量: 481.5
• InChiKey: UGHJCHXWOQBVAP-QZTJIDSGSA-M

计算性质

• 辛醇/水分配系数(LogP)：
  7.5
• 重原子数：
  34
• 可旋转键数：
  8
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.62
• 拓扑面积：
  108
• 氢给体数：
  0
• 氢受体数：
  8

文献信息

• [EN] CANNABINERGIC NITRATE ESTERS AND RELATED ANALOGS<br/>[FR] NITRO-ESTERS CANNABINERGIQUES ET ANALOGUES ASSOCIÉS
  申请人：UNIV NORTHEASTERN

  公开号：WO2014134127A1

  公开（公告）日：2014-09-04

  The present technology relates to novel cannabinergic nitrate esters and related analogs, process of preparation, pharmaceutical compositions and their methods of use as medicaments, pharmacological tools and/or biomarkers. The novel cannabinergic nitrate ester compounds provide medicaments useful in treating a variety of diseases and medical disorders.