N-[2-(furan-2-carbonylcarbamothioylamino)ethylcarbamothioyl]furan-2-carboxamide

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 呋喃
• 英文名称: N-[2-(furan-2-carbonylcarbamothioylamino)ethylcarbamothioyl]furan-2-carboxamide
• 化学式: C₁₄H₁₄N₄O₄S₂
• 分子量: 366.422
• InChiKey: SSVVXFLDEWNXSU-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.5
• 重原子数：
  24
• 可旋转键数：
  5
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.14
• 拓扑面积：
  173
• 氢给体数：
  4
• 氢受体数：
  6

反应信息

• 作为产物：
  描述：

  呋喃甲酰氯 在 polyethylene glycol-400 作用下， 以 二氯甲烷 为溶剂， 反应 2.0h， 生成 N-[2-(furan-2-carbonylcarbamothioylamino)ethylcarbamothioyl]furan-2-carboxamide
  参考文献：
  名称：

  AN EFFICIENT SYNTHESIS OF POLYMETHYLENE-BIS-AROYL THIOUREA DERIVATIVES UNDER THE CONDITION OF PHASE-TRANSFER CATALYSIS

  摘要：

  Reaction of polymethylene diainine with aroyl chloride and ammonium thiocyanate under the condition of solid-liquid phase-transfer catalysis using polyethylene glycol-400 (PEG-400) as the catalyst yielded polymethylene-bis-aroyl thiourea derivatives 3a-q in good-to-excellent yield. The products have been characterized by analytical and spectral (IR and H-1 NMR) data.

  DOI：

  10.1080/10426500490473456

文献信息

• AN EFFICIENT SYNTHESIS OF POLYMETHYLENE-BIS-AROYL THIOUREA DERIVATIVES UNDER THE CONDITION OF PHASE-TRANSFER CATALYSIS
  作者：You-Ming Zhang、Tai-Bao Wei、Liang Xian、Li-Ming Gao

  DOI：10.1080/10426500490473456

  日期：2004.10.1

  Reaction of polymethylene diainine with aroyl chloride and ammonium thiocyanate under the condition of solid-liquid phase-transfer catalysis using polyethylene glycol-400 (PEG-400) as the catalyst yielded polymethylene-bis-aroyl thiourea derivatives 3a-q in good-to-excellent yield. The products have been characterized by analytical and spectral (IR and H-1 NMR) data.