2-[Methyl-[2-[3-(4-methylpiperazin-1-ium-1-ylidene)-6-(4-methylpiperazin-1-yl)xanthen-9-yl]benzoyl]amino]acetic acid

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 苯并吡喃
• 英文名称: 2-[Methyl-[2-[3-(4-methylpiperazin-1-ium-1-ylidene)-6-(4-methylpiperazin-1-yl)xanthen-9-yl]benzoyl]amino]acetic acid
• 英文别名: 2-[methyl-[2-[3-(4-methylpiperazin-1-ium-1-ylidene)-6-(4-methylpiperazin-1-yl)xanthen-9-yl]benzoyl]amino]acetic acid
• 化学式: C33H38N5O4+
• 分子量: 568.7
• InChiKey: OOQSYXDISDTPFM-UHFFFAOYSA-O

计算性质

• 辛醇/水分配系数(LogP)：
  -0.4
• 重原子数：
  42
• 可旋转键数：
  5
• 环数：
  6.0
• sp3杂化的碳原子比例：
  0.36
• 拓扑面积：
  79.6
• 氢给体数：
  1
• 氢受体数：
  7

文献信息

• ACIDIC ENVIRONMENT-DETECTING FLUORESCENT PROBE
  申请人：Urano Yasuteru

  公开号：US20140248654A1

  公开（公告）日：2014-09-04

  Provided is a compound represented by formula (I), which can be used as a fluorescent probe that becomes highly fluorescent only in an intracellular acidic environment and can be adapted to the fluorescent imaging of an intracellular vesicle that is a microstructure. In the formula, R 1 and R 2 independently represent a hydrogen atom, or an alkyl group which may be substituted (wherein R 1 and/or R 2 represents an alkyl group which may be substituted); R 3 , R 4 , R 5 , R 6 , R 7 and R 8 independently represent a hydrogen atom, a halogen atom, or the like; X represents a functional group to which a labeling site or a target-accumulating site can be introduced, or the like; Y represents a halogen atom, an alkyl group which may be substituted, or the like; m represents an integer of 0 to 5; and n represents an integer of 0 to 5.
• US9784732B2
  申请人：——

  公开号：US9784732B2

  公开（公告）日：2017-10-10