NSC 270012 | 65726-77-4

• 分子结构分类: 有机化合物 - 苯类化合物 - 萘
• 英文名称: NSC 270012
• 英文别名: 4-[(1,4-Dioxo-1,4-dihydronaphthalen-2-yl)sulfanyl]butanamide；4-(1,4-dioxonaphthalen-2-yl)sulfanylbutanamide
• CAS: 65726-77-4
• 化学式: C₁₄H₁₃NO₃S
• 分子量: 275.328
• InChiKey: LMMNPEHJTRTXSM-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.2
• 重原子数：
  19
• 可旋转键数：
  5
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.21
• 拓扑面积：
  103
• 氢给体数：
  1
• 氢受体数：
  4

文献信息

• CD45 and Methods and Compounds Related Thereto
  申请人：Panchal Rekha

  公开号：US20120135013A1

  公开（公告）日：2012-05-31

  Disclosed herein are compounds, compositions and methods for preventing, reducing or inhibiting an amount of protein tyrosine phosphatase receptor type C (CD45) expressed or activity of CD45 in a cell or a subject. Also disclosed are methods for preventing, inhibiting or treating an infection in a cell or a subject immunizing a subject or enhancing a subject's immune response against an infection preventing, reducing or inhibiting the susceptibility of a cell or a subject to an infection or subsequent pathogenesis and morbidity due to the infection and preventing, reducing, and inhibiting apoptosis caused by or resulting from a biological agent in a cell or a subject which comprises preventing, reducing or inhibiting an amount of protein tyrosine phosphatase receptor type C (CD45) expressed or activity of CD45 in the cell or the subject.