Pentanoic acid, 5-oxo-5-[[4-(2-phenylethenyl)phenyl]amino]- | 496910-11-3

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 二苯乙烯类
• 英文名称: Pentanoic acid, 5-oxo-5-[[4-(2-phenylethenyl)phenyl]amino]-
• 英文别名: 5-oxo-5-[4-(2-phenylethenyl)anilino]pentanoic acid
• CAS: 496910-11-3
• 化学式: C₁₉H₁₉NO₃
• 分子量: 309.4
• InChiKey: FTXJWRRYLLRFMG-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.2
• 重原子数：
  23
• 可旋转键数：
  7
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.16
• 拓扑面积：
  66.4
• 氢给体数：
  2
• 氢受体数：
  3

文献信息

• Anti-stilbene antibodies
  申请人：——

  公开号：US20040005649A1

  公开（公告）日：2004-01-08

  The present invention provides an anti-stilbene antibody. Preferably, the antibody is a monoclonal antibody. Exemplary and preferred such antibodies are designated herein as 19G2, 20F2, 21C6, 22B9, 25F8, 25E2, 23E4, 23G3, 23D3, 23C2, 25C10, 24B6, 21E2, 16H10 and 9E11. The present invention further provides hybridomas that produce and secrete anti-stilbene antibodies. An antibody of the present invention has particular utility in processes for identifying and/or locating target moieties appended to or incorporating antigenic stilbene. In one embodiment, therefore, the present invention further provides a method of detecting antigenic stilbene. The method includes the steps of exposing antigenic stilbene to an anti-stilbene antibody and detecting an anti-stilbene antibody-stilbene immunoconjugate. Such immunoconjugates can be detected using fluoroscopic procedures.

  本发明提供了一种抗芴基抗体。最好是单克隆抗体。本文中所述的示例和首选抗体被指定为19G2、20F2、21C6、22B9、25F8、25E2、23E4、23G3、23D3、23C2、25C10、24B6、21E2、16H10和9E11。本发明还提供了产生和分泌抗芴基抗体的杂交瘤。本发明的抗体在识别和/或定位附着或包含抗原芴基的靶标分子的过程中具有特定的实用性。因此，在一个实施例中，本发明进一步提供了一种检测抗原芴基的方法。该方法包括将抗原芴基暴露于抗芴基抗体并检测抗芴基抗体-芴基免疫结合物的步骤。这种免疫结合物可以使用荧光显微技术来检测。
• REGULATED BIOCIRCUIT SYSTEMS
  申请人：Obsidian Therapeutics, Inc.

  公开号：US20190192691A1

  公开（公告）日：2019-06-27

  The present invention provides regulatable biocircuit systems. Such systems provide modular and tunable protein expression systems in support of the discovery and development of therapeutic modalities.
• IDENTIFICATION AND TARGETED MODULATION OF GENE SIGNALING NETWORKS
  申请人：CAMP4 THERAPEUTICS CORPORATION

  公开号：US20210254056A1

  公开（公告）日：2021-08-19

  The present invention provides methods and compositions for the evaluation, alteration and/or optimization of gene signaling. Methods and systems are also provided which exploit the information generated in the identification of new targets and non-canonical signaling pathways.