MT-7716 | 1215859-92-9

• 分子结构分类: 有机化合物 - 苯类化合物 - 萘
• 英文名称: MT-7716
• 英文别名: 2-[3-[1-[(1R)-1,2-dihydroacenaphthylen-1-yl]piperidin-4-yl]-2-oxobenzimidazol-1-yl]-N-methylacetamide;hydrate;hydrochloride
• CAS: 1215859-92-9
• 化学式: C27H31ClN4O3
• 分子量: 495.0
• InChiKey: NZSPJWUQIIWTKM-PPLJNSMQSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.23
• 重原子数：
  35
• 可旋转键数：
  4
• 环数：
  6.0
• sp3杂化的碳原子比例：
  0.33
• 拓扑面积：
  56.9
• 氢给体数：
  3
• 氢受体数：
  4

文献信息

• Drug for treating cocaine addiction or preventing recurrence of same
  申请人：MITSUBISHI TANABE PHARMA CORPORATION

  公开号：US11058674B2

  公开（公告）日：2021-07-13

  The present invention provides a drug for treating cocaine addiction or preventing the relapse of the same. Specifically, the present invention provides a drug for treating cocaine addiction or preventing the relapse of the same containing (R)-2-3-[1-(5-methyl-1,2,3,4-tetrahydronaphthalen-1-yl)piperidin-4-yl]-2,3-dihydro-2-oxo-benzimidazol-1-yl}-N-methylacetamide or a pharmaceutically acceptable salt thereof.

  本发明提供了一种用于治疗可卡因成瘾或防止其复发的药物。具体地说，本发明提供了一种治疗可卡因成瘾或防止其复发的药物，其中含有(R)-2-3-[1-(5-甲基-1,2,3,4-四氢萘-1-基)哌啶-4-基]-2,3-二氢-2-氧代-苯并咪唑-1-基}-N-甲基乙酰胺或其药学上可接受的盐。
• DRUG FOR TREATING COCAINE ADDICTION OR PREVENTING RECURRENCE OF SAME
  申请人：MITSUBISHI TANABE PHARMA CORPORATION

  公开号：US20200289492A1

  公开（公告）日：2020-09-17

  The present invention provides a drug for treating cocaine addiction or preventing the relapse of the same. Specifically, the present invention provides a drug for treating cocaine addiction or preventing the relapse of the same containing (R)-2-3-[1-(5-methyl-1,2,3,4-tetrahydronaphthalen-1-yl)piperidin-4-yl]-2,3-dihydro-2-oxo-benzimidazol-1-yl}-N-methylacetamide or a pharmaceutically acceptable salt thereof.