(-)-(S)-4-(3,4-Dihydroxyphenyl)-1,2,3,4-tetrahydro-7,8-isoquinolinediol | 139233-53-7

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 四氢异喹啉
• 英文名称: (-)-(S)-4-(3,4-Dihydroxyphenyl)-1,2,3,4-tetrahydro-7,8-isoquinolinediol
• 英文别名: (4S)-4-(3,4-dihydroxyphenyl)-1,2,3,4-tetrahydroisoquinoline-7,8-diol
• CAS: 139233-53-7
• 化学式: C₁₅H₁₅NO₄
• 分子量: 273.28
• InChiKey: FULLEMQICAKPOE-JTQLQIEISA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.4
• 重原子数：
  20
• 可旋转键数：
  1
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.2
• 拓扑面积：
  93
• 氢给体数：
  5
• 氢受体数：
  5

文献信息

• METHODS AND COMPOSITIONS FOR TREATING CANCER
  申请人：Globavir BioSciences, Inc.

  公开号：US20160361298A1

  公开（公告）日：2016-12-15

  Described are compositions and methods for treating cancer. Some methods comprise the administration of an effective amount of at least one inhibitor of tryptophan 2,3-dioxygenase (TDO) and/or indoleamine 2,3-dioxygenase (IDO), optionally combined with one or more additional anti-cancer agents.
• [EN] METHODS AND COMPOSITIONS FOR TREATING CANCER<br/>[FR] MÉTHODES ET COMPOSITIONS POUR LE TRAITEMENT DU CANCER
  申请人：GLOBAVIR BIOSCIENCES INC

  公开号：WO2016201354A1

  公开（公告）日：2016-12-15

  Described are compositions and methods for treating cancer. Some methods comprise the administration of an effective amount of at least one inhibitor of tryptophan 2, 3-dioxygenase (TDO) and/or indoleamine 2, 3-dioxygenase (IDO), optionally combined with one or more additional anti-cancer agents.