2-(2,4-Ditert-butylphenyl)naphthalene-1,4,5,8-tetracarboxylic acid

• 分子结构分类: 有机化合物 - 苯类化合物 - 萘
• 英文名称: 2-(2,4-Ditert-butylphenyl)naphthalene-1,4,5,8-tetracarboxylic acid
• 英文别名: 2-(2,4-ditert-butylphenyl)naphthalene-1,4,5,8-tetracarboxylic acid
• 化学式: C₂₈H₂₈O₈
• 分子量: 492.5
• InChiKey: RTYOWTTXOPQYRO-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  6.2
• 重原子数：
  36
• 可旋转键数：
  7
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.29
• 拓扑面积：
  149
• 氢给体数：
  4
• 氢受体数：
  8

文献信息

• ASSAY METHODS INVOLVING DISSOCIABLE NANOPARTICLES
  申请人：Selux Diagnostics Inc.

  公开号：EP3172569A1

  公开（公告）日：2017-05-31
• DISSOCIABLE NANOPARTICLES WITH INTER ALIA TRANSITION-METAL COMPLEX CATALYSTS
  申请人：SELUX DIAGNOSTICS, INC.

  公开号：US20190091673A1

  公开（公告）日：2019-03-28

  Nanoparticles for use in assay methods for detecting analytes in samples, which comprise a signal inducing agent, e.g. a transition-metal catalyst or a chemiluminophore, a chemiluminophore precursor, a soluble absorber, or a soluble absorber precursor. After binding to an analyte, the nanoparticle is dissociated by a chemical or physical trigger, e.g. an organic solvent or ultrasound, to release the signal inducing agent, which releases a detectable signal via a physical or chemical reaction. The nanoparticles comprising a chemiluminophore, a chemiluminophore precursor, a soluble absorber, or a soluble absorber precursor can also effect chemical reactions that serve as signal amplifiers.
• [EN] ASSAY METHODS INVOLVING DISSOCIABLE NANOPARTICLES<br/>[FR] PROCÉDÉS D'ANALYSE IMPLIQUANT DES NANOPARTICULES DISSOCIABLES
  申请人：SELUX DIAGNOSTICS INC

  公开号：WO2016015027A1

  公开（公告）日：2016-01-28

  Among other things, the present invention provides assay methods for detecting or quantifying one or more analytes in a sample, which involve the use of dissociable nanoparticles that comprise one or more signaling agents (e.g., the nanoparticles conceal or partially conceal the signaling agents).
• [EN] DISSOCIABLE TRANSITION-METAL NANOPARTICLES<br/>[FR] NANOPARTICULES DE MÉTAL DE TRANSITION DISSOCIABLES
  申请人：SELUX DIAGNOSTICS INC

  公开号：WO2017015145A2

  公开（公告）日：2017-01-26

  Assay methods for detecting analytes in samples involving the use of nanoparticles that comprise a signal inducing agent, e.g., a transition- metal catalyst. After binding to an analyte, the nanoparticle is dissociated by a trigger to release the signal inducing agent, which releases a detectable signal via a physical or chemical reaction. Also described herein are nanoparticles, and compositions and uses thereof, where the nanoparticle comprises chemiluminophore, a chemiluminophore precursor, a soluble absorber, or a soluble absorber precursor, that effects chemical reactions that serve as signal amplifiers.