Potassium 6-(p-toluidino)naphthalene-2-sulphonate | 32752-10-6

• 分子结构分类: 有机化合物 - 苯类化合物 - 萘
• 英文名称: Potassium 6-(p-toluidino)naphthalene-2-sulphonate
• 英文别名: potassium;6-(4-methylanilino)naphthalene-2-sulfonate
• CAS: 32752-10-6
• 化学式: C17H14KNO3S
• 分子量: 351.5
• InChiKey: GVDCHDBOXJUSDZ-UHFFFAOYSA-M

计算性质

• 辛醇/水分配系数(LogP)：
  0.8
• 重原子数：
  23
• 可旋转键数：
  2
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.06
• 拓扑面积：
  77.6
• 氢给体数：
  1
• 氢受体数：
  4

安全信息

• 危险品标志：
  Xi
• 危险类别码：
  R36/37/38
• 海关编码：
  2921499090
• 安全说明：
  S24/25

文献信息

• [EN] REVERSE HEAD GROUP LIPIDS, LIPID PARTICLE COMPOSITIONS COMPRISING REVERSE HEADGROUP LIPIDS, AND METHODS FOR THE DELIVERY OF NUCLEIC ACIDS<br/>[FR] LIPIDES À TÊTES POLAIRES INVERSÉES, COMPOSITIONS PARTICULAIRES LIPIDIQUES COMPRENANT LES LIPIDES À TÊTES POLAIRES INVERSÉES, ET PROCÉDÉS D'ADMINISTRATION D'ACIDES NUCLÉIQUES
  申请人：UNIV BRITISH COLUMBIA

  公开号：WO2011056682A1

  公开（公告）日：2011-05-12

  The present invention related to a novel class of zwitterionic lipids that are useful in the preparation of lipid particles suitable for the delivery of encapsulated nucleic acids to cells.

  本发明涉及一种新型的带电离子脂质类物质，可用于制备适用于将封装的核酸传递至细胞的脂质粒子。
• Optical switch and safety apparatus using the same
  申请人：Fuji Photo Film Co., Ltd.

  公开号：EP1445600A1

  公开（公告）日：2004-08-11

  Provided are optical switches applicable to various safety apparatuses which can control an operation of a circuit by detecting a switching signal such as pathogens and toxic substances, and safety apparatuses using the optical switches. The optical switch comprises an optical irradiation unit to irradiate light; an optical interference unit which can interact with a switching signal, interferes with light irradiated from the optical irradiation unit and radiates it as interference light, and can vary the wavelength of the interference light after interaction with the switching signal; and a switching unit which is provided in the path of the interference light, detects a wavelength change of the interference light, and conducts One of activating and deactivating a circuit. The safety appatatus comprises the optical switch and a hazard evasive apparatus activating unit which activates a hazard evasive apparatus using the optical switch.

  本发明提供了适用于各种安全装置的光开关，它可以通过检测病原体和有毒物质等开关信号来控制电路的运行，还提供了使用光开关的安全装置。光学开关包括：用于照射光的光学照射单元；可与开关信号相互作用的光学干涉单元，干涉从光学照射单元照射的光并将其作为干涉光辐射出去，并且在与开关信号相互作用后可改变干涉光的波长；以及设置在干涉光路径上的开关单元，检测干涉光的波长变化，并执行激活和停用电路的操作。安全装置包括光学开关和危险规避装置激活单元，该单元利用光学开关激活危险规避装置。
• LIPOSOME PREPARATION HAVING HIGH-CONTENT CATIONIC LIPID COMPOUND AND USE THEREOF
  申请人：Biomics Biotechnologies Co., Ltd.

  公开号：EP3443952A1

  公开（公告）日：2019-02-20

  Provided is a liposome for use in the delivery of nucleic acids, comprising a cationic lipid compound, a phospholipid and a long-acting lipid, wherin the weight percentage content of the cationic lipid compound is from 50% to 90%, and the cationic lipid compound is composed of a lipid compound and a cholesterol lipid compound. Also provided are a nucleic acid-liposome preparation comprising the above-mentioned liposome and a nucleic acid encapsulated therein, and a preparation method for the preparation. The content of the nucleic acid drug loaded in the nucleic acid-liposome preparation is comparatively high, and hence, under the conditions of administration of the same dose, the intake amount of the cationic lipid compound relatively decreases, such that the toxicity is lowered.

  本发明提供了一种用于递送核酸的脂质体，由阳离子脂质化合物、磷脂和长效脂质组成，其中阳离子脂质化合物的重量百分比含量为 50%至 90%，阳离子脂质化合物由脂质化合物和胆固醇脂质化合物组成。还提供了一种核酸-脂质体制剂，包括上述脂质体和封装在其中的核酸，以及该制剂的制备方法。该核酸-脂质体制剂中负载的核酸药物含量相对较高，因此在相同剂量给药条件下，阳离子脂质化合物的摄入量相对减少，从而降低了毒性。
• Agent for health inspection and health inspection apparatus using the same
  申请人：FUJI PHOTO FILM CO., LTD.

  公开号：US20020168291A1

  公开（公告）日：2002-11-14

  The agent for health inspection of the present invention is used as additive to a specimen solution and comprises a rod-shaped body and a capturing structured element bonded to the rod-shaped body which specifically captures a disease marker in the specimen solution.

  本发明的健康检测剂可作为标本溶液的添加剂使用，它包括一个棒状体和一个与棒状体粘合的捕捉结构件，该捕捉结构件专门捕捉标本溶液中的疾病标记物。
• Waste water inspecting agent and waste water inspecting apparatus using the same
  申请人：FUJI PHOTO FILM CO., LTD.

  公开号：US20030003476A1

  公开（公告）日：2003-01-02

  A waste water inspecting agent is used as an additive to a specimen solution and comprises a rod-shaped body and a capturing structured element bonded to the rod-shaped body which specifically captures an object to be captured in the specimen solution.

  一种废水检查剂用作试样溶液的添加剂，包括一个棒状体和一个粘接在棒状体上的捕捉结构件，该捕捉结构件专门捕捉试样溶液中的待捕捉物体。

表征谱图