(9-Oxo-9H-xanthen-2-yloxy)-acetic acid

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 苯并吡喃
• 英文名称: (9-Oxo-9H-xanthen-2-yloxy)-acetic acid
• 英文别名: 2-(9-oxoxanthen-2-yl)oxyacetic acid
• 化学式: C₁₅H₁₀O₅
• 分子量: 270.24
• InChiKey: DRKLHCTZOJAHFI-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.2
• 重原子数：
  20
• 可旋转键数：
  3
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.07
• 拓扑面积：
  72.8
• 氢给体数：
  1
• 氢受体数：
  5

文献信息

• Xanthenylamide handle for use in peptide synthesis and methods of producing said handle and support incorporating it
  申请人：REGENTS OF THE UNIVERSITY OF MINNESOTA

  公开号：EP0473411A1

  公开（公告）日：1992-03-04

  The preparation and properties of xanthenylamide handles for use in peptide synthesis is disclosed. The compounds, omega-(9-(9-fluorenylmethyloxycarbonyl)aminoxanthan-2-oxy)alkanoic acid derivatives, are used as peptide handles in the solid phase synthesis of peptide amides. The exemplary compound has the formula wherein n is from about 1 to about 10, and X is OH or the activating group of an active ester or thioester.

  本发明公开了用于肽合成的氧杂苯甲酰胺手柄的制备方法和特性。该化合物是欧米伽-(9-(9-芴甲基氧羰基)氨基黄原酸-2-氧基)烷酸衍生物，可在肽酰胺的固相合成中用作肽柄。示例化合物的化学式为 其中 n 为约 1 至约 10，X 为 OH 或活性酯或硫酯的活化基团。
• COATINGS PREPARED FROM POLY(ETHYLENE OXIDE) AND PHOTO-INITATOR-CONTAINING SCAFFOLDS
  申请人：Coloplast A/S

  公开号：EP2104523A1

  公开（公告）日：2009-09-30
• COATINGS PREPARED FROM POLY(ETHYLENE OXIDE) AND PHOTO-INITIATOR-CONTAINING SCAFFOLDS
  申请人：Coloplast A/S

  公开号：EP2394676B1

  公开（公告）日：2018-03-28
• A MEDICAL DEVICE OF POLYOLEFIN
  申请人：Coloplast A/S

  公开号：EP2459242A2

  公开（公告）日：2012-06-06
• MEDICAL DEVICE OF POLYOLEFIN
  申请人：Nielsen Henrik Lindenskov

  公开号：US20120121919A1

  公开（公告）日：2012-05-17

  The application discloses a method for the preparation (by extruding, injection moulding or powder coating and subsequent cross-linking by irradiation with UV or visible light) of a medical device element involving a coating composition comprising (a) hydrophilic polymer(s) and (b) low molecular weight scaffold(s) having a plurality of photo-initiator moieties covalently linked thereto and/or covalently incorporated therein, wherein the photo-initiator moieties constitute 0.01-20% by weight of the combined amount of the hydrophilic polymer(s) and the low molecular weight scaffolds. The application further discloses such extruded, injection moulded or powder coated medical devices having thereon a layer of a covalently cross-linked coating composition of a hydrophilic polymer and a low molecular weight scaffold having a plurality of residues of photo-initiator moieties.