6-(二甲基氨基)-4-羟基-2-萘羧酸 | 31222-36-3

• 分子结构分类: 有机化合物 - 苯类化合物 - 萘
• 中文名称: 6-(二甲基氨基)-4-羟基-2-萘羧酸
• 英文名称: 6-(dimethylamino)-4-hydroxy-2-naphthoic acid
• 英文别名: 6-Dimethylamino-4-hydroxy-2-naphthoesaeure；6-(Dimethylamino)-4-hydroxy-2-naphthalenecarboxylic acid；6-(dimethylamino)-4-hydroxynaphthalene-2-carboxylic acid
• CAS: 31222-36-3
• 化学式: C₁₃H₁₃NO₃
• 分子量: 231.251
• InChiKey: KBBOOLXWVMMEGP-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.5
• 重原子数：
  17
• 可旋转键数：
  2
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.15
• 拓扑面积：
  60.8
• 氢给体数：
  2
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  甲醇 、 6-(二甲基氨基)-4-羟基-2-萘羧酸 在 硫酸 作用下， 反应 5.0h， 以85 g的产率得到6-(二甲基氨基) -4-羟基-2-萘酸甲酯
  参考文献：
  名称：

  The photophysical behavior of the photochromic naphthopyran derivative having photo-switching ability

  摘要：

  The photophysical behavior of the photochromic naphthopyran derivative 9 with photo-switching ability has been investigated in solution phase as well as in crystalline form. The proposed switching motifs might be a versatile framework in the development of photonic devices whose properties can be toggled between two states on exposure to electromagnetic radiations. The closed form of 9 undergoes reversible transformation upon irradiation with light by changing the molecular structure from ring closed conformation 9 to the ring opened form 10. The compound 9 exhibited first absorption signal at 238 nm with shoulder peak at 261 nm and second absorption signal at 353 nm while on photo-irradiation, the colorless solution of 9 turn to colored and there was ratiometric downfall in the signal intensity for shoulder signal at 261 nm as well as second absorption signal at 353 nm and ultimately results in the disappearance of these both signal after 20 min of irradiations. Meanwhile, the colorimetric change in the reaction solution and considerable shift in the absorption and emission signal intensity as well as position suggest the conformational changes in the molecules from less conjugate conformation 9 to the extended conjugated conformation 10. (C) 2014 Elsevier B.V. All rights reserved.

  DOI：

  10.1016/j.saa.2014.10.016
• 作为产物：
  描述：

  ethyl 4-acetoxy-6-(dimethylamino)-2-naphthoate 在 sodium hydroxide 作用下， 以 乙醇 、 水 为溶剂， 反应 2.0h， 以70 g的产率得到6-(二甲基氨基)-4-羟基-2-萘羧酸
  参考文献：
  名称：

  The photophysical behavior of the photochromic naphthopyran derivative having photo-switching ability

  摘要：

  The photophysical behavior of the photochromic naphthopyran derivative 9 with photo-switching ability has been investigated in solution phase as well as in crystalline form. The proposed switching motifs might be a versatile framework in the development of photonic devices whose properties can be toggled between two states on exposure to electromagnetic radiations. The closed form of 9 undergoes reversible transformation upon irradiation with light by changing the molecular structure from ring closed conformation 9 to the ring opened form 10. The compound 9 exhibited first absorption signal at 238 nm with shoulder peak at 261 nm and second absorption signal at 353 nm while on photo-irradiation, the colorless solution of 9 turn to colored and there was ratiometric downfall in the signal intensity for shoulder signal at 261 nm as well as second absorption signal at 353 nm and ultimately results in the disappearance of these both signal after 20 min of irradiations. Meanwhile, the colorimetric change in the reaction solution and considerable shift in the absorption and emission signal intensity as well as position suggest the conformational changes in the molecules from less conjugate conformation 9 to the extended conjugated conformation 10. (C) 2014 Elsevier B.V. All rights reserved.

  DOI：

  10.1016/j.saa.2014.10.016

文献信息

• Photochromic Polymer and Composition Comprising Photochromic Polymer
  申请人：Evans Richard Alexander

  公开号：US20110147681A1

  公开（公告）日：2011-06-23

  A photochromic polymer comprising at least one siloxane oligomer and at least two photochromic groups covalently linked to one or both terminuses of the siloxane oligomer and compositions containing photochromic siloxane polymers with narrow polydispersity. The photochromic polymer enhances switching speed in rigid host polymers.

  一种光致变色聚合物，包括至少一个硅氧烷寡聚物和至少两个光致变色基团，与硅氧烷寡聚物的一个或两个端点共价连接，并且含有具有狭窄聚分散度的光致变色硅氧烷聚合物的组合物。该光致变色聚合物可以提高刚性主体聚合物的切换速度。
• Fluorescent dye compounds, conjugates and uses thereof
  申请人：Life Technologies Corporation

  公开号：EP2371927A1

  公开（公告）日：2011-10-05

  The present teachings generally relate to fluorescent dyes, linkable forms of fluorescent dyes, energy transfer dyes, reagents labeled with fluorescent dyes and uses thereof.

  本教导一般涉及荧光染料、荧光染料的可连接形式、能量转移染料、用荧光染料标记的试剂及其用途。
• PHOTOCHROMIC POLYMER AND COMPOSITION COMPRISING PHOTOCHROMIC POLYMER
  申请人：Advanced Polymerik Pty Ltd

  公开号：EP2294114A1

  公开（公告）日：2011-03-16
• Fluorescent Dye Compounds, Conjugates and Uses Thereof
  申请人：Graham Ronald J.

  公开号：US20090093062A1

  公开（公告）日：2009-04-09

  The present teachings generally relate to fluorescent dyes, linkable forms of fluorescent dyes, energy transfer dyes, reagents labeled with fluorescent dyes and uses thereof.
• US7256292B2
  申请人：——

  公开号：US7256292B2

  公开（公告）日：2007-08-14