(z)-Diaminostilbene

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 二苯乙烯类
• 英文名称: (z)-Diaminostilbene
• 英文别名: (Z)-1,2-diphenylethene-1,2-diamine
• 化学式: C₁₄H₁₄N₂
• 分子量: 210.27
• InChiKey: TXVWTOBHDDIASC-YPKPFQOOSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.4
• 重原子数：
  16
• 可旋转键数：
  2
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  52
• 氢给体数：
  2
• 氢受体数：
  2

文献信息

• STEREOSELECTIVE METHODS, CATALYSTS AND INTERMEDIATES FOR THE SYNTHESIS OF (-)-NUTLIN-3 AND RELATED COMPOUNDS
  申请人：Johnston Jeffrey N.

  公开号：US20120088915A1

  公开（公告）日：2012-04-12

  The present invention provides methods and intermediates are provided for the preparation of (−)-Nutlin-3. Methods and intermediates are also provided for the enantioselective addition of aryl nitromethanes to aldimines. Bis(amidine) catalysts for the use in these and other reactions are also provided.

  本发明提供了用于制备(−)-Nutlin-3的方法和中间体。还提供了用于对芳基硝基甲烷与醛亚胺进行对映选择性加成的方法和中间体。此外，还提供了用于这些及其他反应中使用的双(胺基)催化剂。
• [EN] BIFUNCTIONAL NUTLIN-LENALIDOMIDE DERIVATIVES ((4,5-DIHYDRO-1H-IMIDAZOLE-1-CARBONYL)PIPERAZIN-1-YL-[LINKER]-1-OXOISOINDOLIN-2-YL)PIPERIDINE-2,6-DIONE DERIVATIVES) AS MDM2 DEGRADERS AND MDM2-P53 INHIBITORS FOR USE IN CANCER THERAPY<br/>[FR] DÉRIVÉS BIFONCTIONNELS DE NUTLINE-LÉNALIDOMIDE (DÉRIVÉS DE LA (4,5-DIHYDRO-1H-IMIDAZOLE-1-CARBONYL)PIPÉRAZIN-1-YL-[LIEUR]-1-OXOISOINDOLIN-2-YL)PIPÉRIDINE-2,6-DIONE) UTILISÉS COMME AGENTS DE DÉGRADATION DE MDM2 ET COMME INHIBITEURS DE MDM2-P53 DESTINÉS À ÊTRE UTILISÉS DANS LE TRAITEMENT DU CANCER
  申请人：WISCONSIN ALUMNI RES FOUND

  公开号：WO2020232115A1

  公开（公告）日：2020-11-19

  Bifunctional nutlin-lenalidomide derivatives ((4,5-dihydro-lH- imidazole-l-carbonyl) piperazin-l-yl-[linker]-l-oxoisoindolin-2-yl) piperidine-2, 6-dione derivatives) of the formula (I),as MDM2 (murine double minute 2) degraders and MDM2-p53 interaction inhibitors for use in inhibiting neoplastic cell growth and cancer therapy

  双功能nutlin-lenalidomide衍生物((4,5-二氢-lH-咪唑-1-羰基)哌嗪-1-基-[连接剂]-1-氧代异吲哚-2-基)哌啶-2,6-二酮衍生物)的化学式(I)，作为MDM2 (murine double minute 2)降解剂和MDM2-p53相互作用抑制剂，用于抑制肿瘤细胞生长和癌症治疗。
• CUCURBITURIL-CONTAINING GEL AND METHOD OF PREPARING THE SAME
  申请人：KIM Kimoon

  公开号：US20070154553A1

  公开（公告）日：2007-07-05

  Provided are a gel including a compound represented by Formula 1 below and a method of preparing the same: wherein n, X, A 1 , and A 2 are as defined in the specification.

  提供了一种含有以下式子1所表示的化合物的凝胶以及其制备方法：其中n，X，A1和A2如说明书所定义。
• Organometallic Complex, and Light-Emitting Element, Light-Emitting Device, and Electronic Device Including the Organometallic Complex
  申请人：Inoue Hideko

  公开号：US20100105902A1

  公开（公告）日：2010-04-29

  An organometallic complex is provided by which favorable red-color light emission can be obtained. Further, an organometallic complex having a peak of light emission at about 620 nm is provided because the wavelength of light which is perceived as excellent red-color light is about 620 nm. Furthermore, an organometallic complex is provided by which red-color light emission with high luminous efficiency (cd/A) can be obtained. An organometallic complex represented by the following general formula (G2) and a light-emitting element, a light-emitting device, and an electronic device including the organometallic complex represented by the following general formula (G2) are provided.

  提供了一种有机金属配合物，可以获得有利的红色光发射。此外，提供了一种具有光发射峰值约为620纳米的有机金属配合物，因为被认为是优秀的红色光的波长约为620纳米。此外，提供了一种可以获得高发光效率（cd/A）的红色光发射的有机金属配合物。提供了以下通式（G2）所代表的有机金属配合物以及包括该有机金属配合物的发光元件、发光装置和电子装置。
• ORGANIC ELECTRONIC DEVICE
  申请人：Novaled GmbH

  公开号：EP2718978B1

  公开（公告）日：2018-05-16